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    Origins and Progression of Adolescent Endometriosis

    Accumulating evidence indicates that adolescent endometriosis is common and often severe. Here we explore the possibility that seeding of naive endometrial progenitor cells into the pelvic cavity early in life...

    Ivo Brosens MD, PhD, Caroline E. Gargett PhD in Reproductive Sciences (2016)

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    Role of Label-Retaining Cells in Estrogen-Induced Endometrial Regeneration

    Candidate stem/progenitor cells have been identified in mouse endometrium as label-retaining cells (LRCs). The role of endometrial stem/progenitor cells in initiating estrogen-stimulated endometrial growth in ...

    Rachel W. S. Chan PhD, Tu’uhevaha Kaitu’u-Lino PhD in Reproductive Sciences (2012)

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    Priorities for Endometriosis Research: Recommendations From an International Consensus Workshop

    Endometriosis is an estrogen-dependent disorder where endometrial tissue forms lesions outside the uterus. Endometriosis affects an estimated 10% of women in the reproductive-age group, rising to 30% to 50% in...

    Peter A. W. Rogers BSc, PhD, Thomas M. D’Hooghe MD, PhD in Reproductive Sciences (2009)

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    Stem Cells in Human Reproduction

    The derivation of human embryonic stem (hES) cells heralds a new era in stem cell research, generating excitement for their therapeutic potential in regenerative medicine. Pioneering work of embryologists, dev...

    Caroline E. Gargett PhD in Reproductive Sciences (2007)

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    Expression of Steroid Receptor Coactivators in Cultured Cells From Paired Myometrial and Fibroid Tissues

    Fibroid tumor growth in the myometrium appears to be regulated by estrogens but the role of estrogen receptor (ER) coregulators, such as the steroid receptor coactivator (SRC) family members, in fibroid growth...

    Sonay Hussein-Fikret BSc (Hons) in The Journal of the Society for Gynecologic… (2005)

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    Estrogen Receptor-α Agonists Promote Angiogenesis in Human Myometrial Microvascular Endothelial Cells

    The relative role of the two estrogen receptors, ERα and ERβ, in mediating angiogenic responses in adult human endothelium is unknown. Tlte aim of this study was to determine whether novel ERα-selective agonis...

    Marina Zaitseva BSc, Doris Sam Yue BSc in The Journal of the Society for Gynecologic… (2004)