188 Result(s)
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Life Sciences
Cell Biology
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Article
Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts
It has been suggested that overexpression of the Bcl-2 oncoprotein in human cancer cells contributes to their resistance to apoptosis induced by chemotherapy. We report here that a novel dipeptidyl proteasome ...
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Article
Function and regulation of Aurora/Ipl1p kinase family in cell division
During mitosis, the parent cell distributes its genetic materials equally into two daughter cells through chromosome segregation, a complex movements orchestrated by mitotic kinases and its effector proteins. ...
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Article
Dynamic distribution of TTK in HeLa cells: insights from an ultrastructural study
Entry into mitosis is driven by signaling cascades of mitotic kinases. Our recent studies show that TTK, a kinetochore-associated protein kinase, interacts with CENP-E, a mitotic kinesin located to corona fibe...
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Article
Genome constitutions of Hystrix patula, H. duthiei ssp. duthiei and H. duthiei ssp. longearistata (Poaceae: Triticeae) revealed by meiotic pairing behavior and genomic in-situ hybridization
Genomic constitutions of three taxa of Hystrix Moench, H. patula, H. duthiei ssp. duthiei and H. duthiei ssp. longearistata, were examined by meiotic pairing behavior and genomic in-situ hybridization. Meiotic pa...
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Chapter
Mitotic Chromosome Segregation Control
The somatic division, called mitosis, is characterized by equal distribution of parental genome into two daughter cells. Mitosis involves a dramatic reorganization of both nucleus and cytoplasm driven by prote...
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Article
Corneal epithelial changes following reconstruction by transplantation of limbal stem cells in goats with total limbal stem cell deficiency
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Article
Fetal porcine mesenchymal stem cells nuclear transfer and isolation of embryonic stem cells-like derived from cloned blastocysts
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Article
Characterization of growth and differentiation of goat limbal adult stem cells in vivo and ex vivo
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Article
Serum free culture and characterization of human embryonic germ cells
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Article
Isolation and characterization of mouse embryonic stem cell line by parthenogenesis
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Article
Reconstruction of corneal epithelium with cryopreserved corneal limbal stem cells in a goat model
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Article
Knock-down Nanog gene expression by siRNA affects the differentiation of cardiomyocytes in P19 cell
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Article
Transplantation of ex vivo expanded stem cell amniotic sheet for ocular surface reconstruction
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Article
Evaluation of the eco-environmental frangibility in west Jilin Province based on the matter-element model
The west Jilin Province is a typical area in the ecotone between agriculture and animal husbandry, with a frangible eco-environment. With respect to the three aspects of water resource, natural disasters and l...
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Article
Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin
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Article
Physiological levels of ATP negatively regulate proteasome function
Intracellular protein degradation by the ubiquitin-proteasome system is ATP dependent, and the optimal ATP concentration to activate proteasome function in vitro is ∼100 μM. Intracellular ATP levels are generally...
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Article
Convenient and Efficient Enrichment of the CD133+ Liver Cells from Rat Fetal Liver Cells as a Source of Liver Stem/Progenitor Cells
Although the stem cells are commonly isolated by FACS or MACS, they are very expensive and these is no specific marker for liver stem/progentior cells (LSPCs). This paper applied a convenient and efficient met...
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Article
Transplanted Late Outgrowth Endothelial Progenitor Cells as Cell Therapy Product for Stroke
Endothelial progenitor cells (EPCs) seem to be a promising option to treat patients with ischemic diseases. Here, we investigated the effects of late outgrowth EPCs, or endothelial colony-forming cells (ECFCs)...
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Article
Tissue distribution and expression of signaling lymphocyte activation molecule receptor to peste des petits ruminant virus in goats detected by real-time PCR
In the present study, we investigated the tissue distribution and expression of signaling lymphocyte activation molecule (SLAM) in 40 tissues and organs of goats by real-time RT-PCR, in order to determine the ...
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Protocol
Convenient and Efficient Enrichment of the CD133+ Liver Cells from Rat Fetal Liver as a Source of Liver Stem/Progenitor Cells
Although stem cells are commonly isolated by fluorescence-activated cell sorting or magnetic affinity cell sorting, they are very expensive, and they need known markers. However, there is no specific marker fo...
