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  1. Article

    Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis

    Chromosome segregation in mitosis is orchestrated by the interaction of the kinetochore with spindle microtubules. Our recent study shows that NEK2A interacts with MAD1 at the kinetochore and possibly function...

    Guosheng Fu, **a Ding, Kai Yuan, Felix Aikhionbare, Jianhui Yao, **n Cai… in Cell Research (2007)

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    Mitotic Chromosome Segregation Control

    The somatic division, called mitosis, is characterized by equal distribution of parental genome into two daughter cells. Mitosis involves a dramatic reorganization of both nucleus and cytoplasm driven by prote...

    Yu Xue, Chuanhai Fu, Yong Miao, Jianhui Yao, Zhen Dou, Jie Zhang… in Nuclear Dynamics (2007)

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    Functions of spindle check-point and its relationship to chromosome instability

    It is generally believed that the equal distribution of genetic materials to two daughter cells during mitosis is the key to cell health and development. During the dynamic process, spindle checkpoint plays a ...

    Jianhui Yao, Yupeng Zheng, Xuebiao Yao in Chinese Science Bulletin (2002)