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Article
Deficiency of Factor XIII Gene in Chinese: 3 Novel Mutations
A defect in the factor XIII gene can result in lifelong bleeding tendency. In 3 Chinese families, hereditary coagulation factor XIII deficiency was diagnosed on the basis of the clinical syndrome and solubilit...
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Article
HIPK2 suppresses tumor growth and progression of hepatocellular carcinoma through promoting the degradation of HIF-1α
Aberrant angiogenesis of hepatocellular carcinoma (HCC) leads to tumor growth and local or distant metastasis. Uncovering the underlying mechanisms for the neoangiogenesis of HCC can provide novel potential th...
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Article
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
There is an urgent need to create novel models using human disease-relevant cells to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) biology and to facilitate drug screening. Here, as SARS-C...
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Chapter and Conference Paper
A Problem-Driven Discussion Teaching Method Based on Progressive Cycle
The problem-driven discussion teaching method is that in the process of teaching, according to the objective law of the learning process, teachers adopt the methods of asking questions, inspiration and guidanc...
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Article
On vanishing near corners of conductive transmission eigenfunctions
This paper is concerned with the geometric structure of the transmission eigenvalue problem associated with a general conductive transmission condition. We prove that under a mild regularity condition in terms...
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Article
Open AccessIntegrative analysis of transcriptomics and metabolomics to reveal the melanogenesis pathway of muscle and related meat characters in Wuliangshan black-boned chickens
Melanin is an important antioxidant in food and has been used in medicine and cosmetology. Chicken meat with high melanin content from black-boned chickens have been considered a high nutritious food with pote...
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Article
Microsatellite analysis of genetic diversity in wild and cultivated Portunus trituberculatus in Bohai Bay
Previous studies have revealed a reduction in the genetic diversity of P. trituberculatus in Bohai Sea. However, because swimming crabs have been released into this area for some time, it is unclear whether the r...
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Article
Open AccessA multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection
COVID-19 is a systemic disease involving multiple organs. We previously established a platform to derive organoids and cells from human pluripotent stem cells to model SARS-CoV-2 infection and perform drug scr...
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Article
Open AccessMicrosatellite markers reveal genetic diversity and population structure of Portunus trituberculatus in the Bohai Sea, China
The swimming crab, Portunus trituberculatus, is one of the main aquaculture species in Chinese coastal regions due to its palatability and high economic value. To obtain a better understanding of the genetic dive...
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Article
Reversible robust fragile multi-watermarking scheme for color images
This research introduced a reversible multi-watermarking scheme for color images with robustness and fragility. The robust watermarking can be used for copyright protection while the fragile watermarking is us...
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Article
Open AccessCheckpoint kinase 2 controls insulin secretion and glucose homeostasis
After the discovery of insulin, a century ago, extensive work has been done to unravel the molecular network regulating insulin secretion. Here we performed a chemical screen and identified AZD7762, a compound...
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Article
Author Correction: Identification of SARS-CoV-2 inhibitors using lung and colonic organoids