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Article
Open AccessInflammasome activity is controlled by ZBTB16-dependent SUMOylation of ASC
Inflammasome activity is important for the immune response and is instrumental in numerous clinical conditions. Here we identify a mechanism that modulates the central Caspase-1 and NLR (Nod-like receptor) ada...
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Article
Fracture toughness and destructive mechanism of ductile nanoporous metallic glass and its crystal-impregnated nanocomposite
Nanoporous metallic glasses (NPMGs) and crystalline/amorphous nanocomposites exhibit superior ductility over bulk macroscopic metallic glasses (MGs). Their fracture behaviors remain a mystery due to experiment...
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Article
TESC promotes differentiated thyroid cancer development by activating ERK and weakening NIS and radioiodine uptake
Most differentiated thyroid cancer (DTC) patients have a good prognosis after surgery, but radioiodine refractory differentiated thyroid cancer (RAIR-DTC) patients have a significantly reduced 5-year survival ...
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Article
Open AccessPenile surgery for patients with Peyronie’s disease initially treated with collagenase clostridium histolyticum or surgery: a claims database analysis
Collagenase clostridium histolyticum (CCH) is an injectable therapy targeting collagen present in penile plaques in Peyronie’s disease (PD). Data comparing CCH to penile surgery are limited, and long-term ther...
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Article
Nanoindentation characteristics of nanocrystalline B2 CuZr shape memory alloy via large-scale atomistic simulation
Nanoindentation tests are performed by molecular dynamics simulation to explore the mechanical properties of nanocrystalline B2 CuZr shape memory alloys with average grain sizes ranging from 6 to 18 nm. Some p...
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Article
Open AccessCell graph neural networks enable the precise prediction of patient survival in gastric cancer
Gastric cancer is one of the deadliest cancers worldwide. An accurate prognosis is essential for effective clinical assessment and treatment. Spatial patterns in the tumor microenvironment (TME) are conceptual...
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Article
Open AccessDecreased serum iron concentration and total iron binding capacity are associated with serious Crohn’s disease
This study aimed to investigate whether serum indicators related to iron stores in the body are associated with clinical and endoscopic disease severity. Eighty-four patients with Crohn’s disease (CD) and twen...
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Article
Cold welding behavior of metallic glass nanowires: Insights from large-scale numerical simulations
Cold welding technique at room temperature is the preferred option in nano-assembly and nano-jointing. In this study, the cold welding behavior and mechanical strength of Cu50Zr50 metallic glass nanowires (MGNWs)...
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Article
Silencing of an aquaporin gene diminishes bacterial blight disease in rice
The translocation of type III effectors of plant-pathogenic bacteria is required both for the expression of their role in virulence, and for the triggering of plant defenses. The effector translocation needs m...
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Article
Open AccessTwo virulent sRNAs identified by genomic sequencing target the type III secretion system in rice bacterial blight pathogen
Small non-coding RNA (sRNA) short sequences regulate various biological processes in all organisms, including bacteria that are animal or plant pathogens. Virulent or pathogenicity-associated sRNAs have been i...
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Chapter and Conference Paper
Single Image Super Resolution via Neighbor Reconstruction
Super Resolution (SR) is a complex, ill-posed problem where the aim is to construct the map** between the low and high resolution manifolds of image patches. Anchored neighborhood regression for SR (namely A+ [
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Article
Open AccessIdentification of a histone family gene signature for predicting the prognosis of cervical cancer patients
Heterogeneity in terms of tumor characteristics, prognosis, and survival among cancer patients is an unsolved issue. Here, we systematically analyzed the aberrant expression patterns of cervical cancer using R...
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Article
Open AccessUnderstanding immune phenotypes in human gastric disease tissues by multiplexed immunohistochemistry
Understanding immune phenotypes and human gastric disease in situ requires an approach that leverages multiplexed immunohistochemistry (mIHC) with multispectral imaging to facilitate precise image analyses.
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Article
Quantum Multi-Image Encryption Based on Iteration Arnold Transform with Parameters and Image Correlation Decomposition
A novel quantum multi-image encryption algorithm based on iteration Arnold transform with parameters and image correlation decomposition is proposed, and a quantum realization of the iteration Arnold transform...
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Article
Quantum image encryption scheme with iterative generalized Arnold transforms and quantum image cycle shift operations
A new quantum image encryption scheme is suggested by using the iterative generalized Arnold transforms and the quantum image cycle shift operations. The times of the quantum image cycle shift operations are c...
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Chapter
Emerging Roles for Epigenetic Programming in the Control of Inflammatory Signaling Integration in Heath and Disease
Macrophages and dendritic cells initiate the innate immune response to infection and injury and contribute to inflammatory signaling to maintain the homeostasis of various tissues, which includes resident macr...
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Chapter
Roles of HDACs in the Responses of Innate Immune Cells and as Targets in Inflammatory Diseases
Histone deacetylases (HDACs) are an emerging class of molecules involved in the epigenetic regulation of innate immune responses through Toll-like receptor (TLR) and interferon (IFN) signaling pathways. HDACs ...
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Article
Open AccessCD14 and IL18 gene polymorphisms associated with colorectal cancer subsite risks among atomic bomb survivors
Colorectal cancer (CRC) is a common malignancy worldwide, and chronic inflammation is a risk factor for CRC. In this study, we carried out a cohort study among the Japanese atomic bomb (A-bomb) survivor popula...
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Chapter and Conference Paper
Sustained Observability for Salient Motion Detection
Detection of the motion of foreground objects on the backdrop of constantly changing and complex visuals has always been challenging. The motion of foreground objects, which is termed as salient motion, is mar...
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Chapter and Conference Paper
Unsupervised Feature Selection for Salient Object Detection
Feature selection plays a crucial role in deciding the salient regions of an image as in any other pattern recognition problem. However the problem of identifying the relevant features that plays a fundamental...
