41 Result(s)
within
**ao-ling Huang
Science, Humanities and Social Sciences, multidisciplinary
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Article
Probing the nature of gold–carbon bonding in gold–alkynyl complexes
Homogeneous catalysis by gold involves organogold complexes as precatalysts and reaction intermediates. Fundamental knowledge of the gold–carbon bonding is critical to understanding the catalytic mechanisms. H...
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Article
Open AccessContinuous-flow Mass Production of Silicon Nanowires via Substrate-Enhanced Metal-Catalyzed Electroless Etching of Silicon with Dissolved Oxygen as an Oxidant
Silicon nanowires (SiNWs) are attracting growing interest due to their unique properties and promising applications in photovoltaic devices, thermoelectric devices, lithium-ion batteries and biotechnology. Low...
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Article
Open AccessReal-Time Light Scattering Tracking of Gold Nanoparticles- bioconjugated Respiratory Syncytial Virus Infecting HEp-2 Cells
Real-time tracking of virus invasion is crucial for understanding viral infection mechanism, which, however, needs simple and efficient labeling chemistry with improved signal-to-noise ratio. For that purpose,...
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Article
Open AccessUtilisation of adsorption and desorption for simultaneously improving protein crystallisation success rate and crystal quality
High-quality protein crystals of suitable size are an important prerequisite for applying X-ray crystallography to determine the 3-dimensional structure of proteins. However, it is often difficult to obtain pr...
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Article
Open AccessHigh Maternal Serum Estradiol Levels Induce Dyslipidemia in Human Newborns via a Hepatic HMGCR Estrogen Response Element
While the intrauterine environment is essential for the health of offspring, the impact of high maternal serum estradiol (E2) on lipid metabolism in offspring and the mechanisms are unknown. We found that ovarian...
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Article
Open AccessPNPLA3 genetic variants determine hepatic steatosis in non-obese chronic hepatitis C patients
The influence of patatin-like phospholipase domain-containing 3 (PNPLA3) genetic variants in the development of liver steatosis in Asian chronic hepatitis C patients remains elusive. A total of 1018 biopsy-proven...
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Article
Open AccessRegulation of Transcription Factor Yin Yang 1 by SET7/9-mediated Lysine Methylation
Yin Yang 1 (YY1) is a multifunctional transcription factor shown to be critical in a variety of biological processes. Although it is regulated by multiple types of post-translational modifications (PTMs), whet...
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Article
Open AccessSuperior thermoelasticity and shape-memory nanopores in a porous supramolecular organic framework
Flexible porous materials generally switch their structures in response to guest removal or incorporation. However, the design of porous materials with empty shape-switchable pores remains a formidable challen...
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Article
Open AccessPharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis
Lysophosphatidic acid (LPA), a growth factor-like phospholipid, regulates numerous physiological functions, including cell proliferation and differentiation. In a previous study, we have demonstrated that LPA ...
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Article
Open AccessIdentification and testing of oviposition attractant chemical compounds for Musca domestica
Oviposition attractants for the house fly Musca domestica have been investigated using electrophysiological tests, behavioural assays and field tests. Volatiles were collected via head space absorption method fro...
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Article
Open AccessClinical and genetic analyses reveal novel pathogenic ABCA4 mutations in Stargardt disease families
Stargardt disease (STGD1) is a juvenile macular degeneration predominantly inherited in an autosomal recessive pattern, characterized by decreased central vision in the first 2 decades of life. The condition h...
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Article
Open AccessLipoprotein-biomimetic nanostructure enables efficient targeting delivery of siRNA to Ras-activated glioblastoma cells via macropinocytosis
Hyperactivated Ras regulates many oncogenic pathways in several malignant human cancers including glioblastoma and it is an attractive target for cancer therapies. Ras activation in cancer cells drives protein in...
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Article
Open AccessSelective serotonin reuptake inhibitor, fluoxetine, impairs E-cadherin-mediated cell adhesion and alters calcium homeostasis in pancreatic beta cells
Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed drugs for mood disorders. Long term use of SSRIs is associated with an increased risk of diabetes, but the underlying mechanism(...
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Article
Open AccessGenome-wide identification of Major Intrinsic Proteins in Glycine soja and characterization of GmTIP2;1 function under salt and water stress
In different plant species, aquaporins (AQPs) facilitate water movement by regulating root hydraulic conductivity under diverse stress conditions such as salt and water stresses. To improve survival and yield ...
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Article
Open AccessCaMKII-mediated Beclin 1 phosphorylation regulates autophagy that promotes degradation of Id and neuroblastoma cell differentiation
Autophagy is a degradative pathway that delivers cellular components to the lysosome for degradation. The role of autophagy in cell differentiation is poorly understood. Here we show that CaMKII can directly p...
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Article
Open AccessRegulation of ethylene-responsive SlWRKYs involved in color change during tomato fruit ripening
WRKY transcription factors (TFs) play important roles in stress responses in planta. However, the function of WRKY TFs in the regulation of fruit ripening is unclear. Here, 23 tomato SlWRKYs that are similar to e...
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Article
Open AccessDelivery of xenon-containing echogenic liposomes inhibits early brain injury following subarachnoid hemorrhage
Xenon (Xe), a noble gas, has promising neuroprotective properties with no proven adverse side-effects. We evaluated neuroprotective effects of Xe delivered by Xe-containing echogenic liposomes (Xe-ELIP) via ul...
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Article
Correction: Publisher Correction: Probing the nature of gold–carbon bonding in gold–alkynyl complexes
Nature Communications 4: Article number: 2223 (2013), Published 26 July 2013; Updated 29 March 2018 The original HTML version of this Article had an incorrect article number of 2201; it should have been 2223. ...
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Article
Open AccessElovl6 is a negative clinical predictor for liver cancer and knockdown of Elovl6 reduces murine liver cancer progression
The elongation of long-chain fatty acids family member 6 (Elovl6) is a key enzyme in lipogenesis that catalyzes the elongation of saturated and monounsaturated fatty acids. Insulin resistance involves upregula...
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Article
Open AccessN-methyl D-aspartate receptor subtype 2B antagonist, Ro 25-6981, attenuates neuropathic pain by inhibiting postsynaptic density 95 expression
Postsynaptic density-95 (PSD-95) is a synaptic scaffolding protein that plays a crucial role in the development of neuropathic pain. However, the underlying mechanism remains unclear. To address the role of PS...
