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  1. Article

    Open Access

    Mitotic phosphorylation of tumor suppressor DAB2IP maintains spindle assembly checkpoint and chromosomal stability through activating PLK1-Mps1 signal pathway and stabilizing mitotic checkpoint complex

    Chromosomal instability (CIN) is a driving force for cancer development. The most common causes of CIN include the dysregulation of the spindle assembly checkpoint (SAC), which is a surveillance mechanism that...

    Lan Yu, Yue Lang, Ching-Cheng Hsu, Wei-Min Chen, Jui-Chung Chiang in Oncogene (2022)

  2. Article

    Open Access

    Pharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis

    Lysophosphatidic acid (LPA), a growth factor-like phospholipid, regulates numerous physiological functions, including cell proliferation and differentiation. In a previous study, we have demonstrated that LPA ...

    Kuan-Hung Lin, Ya-Hsuan Ho, Jui-Chung Chiang, Meng-Wei Li in Scientific Reports (2016)