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    Sonogenetic Modulation of Cellular Activities in Mammalian Cells

    Ultrasound is acoustic waves that can penetrate deeply into tissue in a focused manner with limited adverse effects on cells. As such, ultrasound has been widely used for clinical diagnosis for several decades...

    Yao-Shen Huang, Ching-Hsiang Fan, Wei-Ting Yang in Mammalian Cell Engineering (2021)

  2. Article

    Open Access

    Spatiotemporal manipulation of ciliary glutamylation reveals its roles in intraciliary trafficking and Hedgehog signaling

    Tubulin post-translational modifications (PTMs) occur spatiotemporally throughout cells and are suggested to be involved in a wide range of cellular activities. However, the complexity and dynamic distribution...

    Shi-Rong Hong, Cuei-Ling Wang, Yao-Shen Huang, Yu-Chen Chang in Nature Communications (2018)

  3. Article

    Open Access

    Elovl6 is a negative clinical predictor for liver cancer and knockdown of Elovl6 reduces murine liver cancer progression

    The elongation of long-chain fatty acids family member 6 (Elovl6) is a key enzyme in lipogenesis that catalyzes the elongation of saturated and monounsaturated fatty acids. Insulin resistance involves upregula...

    Yu-Chu Su, Yin-Hsun Feng, Hung-Tsung Wu, Yao-Shen Huang in Scientific Reports (2018)