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Open AccessAssociations of clinical subtypes and bile acid levels of intrahepatic cholestasis of pregnancy with pregnancy outcomes
Intrahepatic cholestasis of pregnancy (ICP) can lead to many adverse pregnancy outcomes, and the influencing factors remain unclear at present. This study retrospectively analyzed clinical data from 1815 pregn...
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Article
Open AccessEnhanced risk of record-breaking regional temperatures during the 2023–24 El Niño
In 2023, the development of El Niño is poised to drive a global upsurge in surface air temperatures (SAT), potentially resulting in unprecedented warming worldwide. Nevertheless, the regional patterns of SAT a...
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Article
Open AccessCross-talk between disulfidptosis and immune check point genes defines the tumor microenvironment for the prediction of prognosis and immunotherapies in glioblastoma
Disulfidptosis is a condition where dysregulated NAPDH levels and abnormal accumulation of cystine and other disulfides occur in cells with high SLC7A11 expression under glucose deficiency. This disrupts norma...
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Open AccessMiddle east warming in spring enhances summer rainfall over Pakistan
The edge of a monsoon region is usually highly sensitive to climate change. Pakistan, which is located on the northern edge of the Indian monsoon, is highly vulnerable to heavy rainfall and has witnessed sever...
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Open AccessReversed asymmetric warming of sub-diurnal temperature over land during recent decades
In the latter half of the twentieth century, a significant climate phenomenon “diurnal asymmetric warming” emerged, wherein global land surface temperatures increased more rapidly during the night than during ...
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Open AccessRobust projection of East Asian summer monsoon rainfall based on dynamical modes of variability
The Asian monsoon provides the freshwater that a large population in Asia depends on, but how anthropogenic climate warming may alter this key water source remains unclear. This is partly due to the prevailing...
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Article
Open AccessIncreased impact of heat domes on 2021-like heat extremes in North America under global warming
During summer 2021, Western North America (WNA) experienced an unprecedented heatwave with record-breaking high temperatures associated with a strong anomalous high-pressure system, i.e., a heat dome. Here, we...
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Open AccessConstraining extreme precipitation projections using past precipitation variability
Projected changes of future precipitation extremes exhibit substantial uncertainties among climate models, posing grand challenges to climate actions and adaptation planning. Practical methods for narrowing th...
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Open AccessMitigation of China’s carbon neutrality to global warming
Projecting mitigations of carbon neutrality from individual countries in relation to future global warming is of great importance for depicting national climate responsibility but is poorly quantified. Here, w...
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Open AccessObservationally constrained projection of Afro-Asian monsoon precipitation
The Afro-Asian summer monsoon (AfroASM) sustains billions of people living in many develo** countries covering West Africa and Asia, vulnerable to climate change. Future increase in AfroASM precipitation has...
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Article
Open AccessAtomic structure of a seed-sized gold nanoprism
The growth of nanoparticles along one or two directions leads to anisotropic nanoparticles, but the nucleation (i.e., the formation of small seeds of specific shape) has long been elusive. Here, we show the to...
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Article
Open AccessA very likely weakening of Pacific Walker Circulation in constrained near-future projections
The observational records have shown a strengthening of the Pacific Walker circulation (PWC) since 1979. However, whether the observed change is forced by external forcing or internal variability remains incon...
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Article
Open AccessEmergent constraints on future projections of the western North Pacific Subtropical High
The western North Pacific Subtropical High (WNPSH) is a key circulation system controlling the summer monsoon and typhoon activities over the western Pacific, but future projections of its changes remain hugel...
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Open AccessAtomically resolved Au52Cu72(SR)55 nanoalloy reveals Marks decahedron truncation and Penrose tiling surface
Gold-copper alloys have rich forms. Here we report an atomically resolved [Au52Cu72(p-MBT)55]+Cl− nanoalloy (p-MBT = SPh-p-CH3). This nanoalloy exhibits unusual structural patterns. First, two Cu atoms are locate...
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Open AccessNatural drivers of multidecadal Arctic sea ice variability over the last millennium
The climate varies due to human activity, natural climate cycles, and natural events external to the climate system. Understanding the different roles played by these drivers of variability is fundamental to p...
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Open AccessReduced exposure to extreme precipitation from 0.5 °C less warming in global land monsoon regions
The Paris Agreement set a goal to keep global warming well below 2 °C and pursue efforts to limit it to 1.5 °C. Understanding how 0.5 °C less warming reduces impacts and risks is key for climate policies. Here...
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Open AccessIn-situ liquid cell transmission electron microscopy investigation on oriented attachment of gold nanoparticles
Inside a liquid solution, oriented attachment (OA) is now recognized to be as important a pathway to crystal growth as other, more conventional growth mechanisms. However, the driving force that controls the o...
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Article
Open AccessAtmospheric footprint of the recent warming slowdown
Growing body of literature has developed to detect the role of ocean heat uptake and transport in the recent warming slowdown between 1998–2013; however, the atmospheric footprint of the slowdown in dynamical ...
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Article
Open AccessThe Identification and Characterization of Two Novel Epitopes on the Nucleocapsid Protein of the Porcine Epidemic Diarrhea Virus
Porcine epidemic diarrhea virus (PEDV) is a highly contagious coronavirus that causes severe diarrhea and death, particularly in neonatal piglets. The nucleocapsid protein (N protein) of PEDV presents strong immu...
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Open AccessEnterohemorrhagic Escherichia coli promotes the invasion and tissue damage of enterocytes infected with Candida albicans in vitro
The principal aim of this study was to investigate the in vitro co-infection of Caco-2 cells with Candida albicans and enterohemorrhage Escherichia coli (EHEC). The ability of both species to colonize or invade t...