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Article
Open AccessPartial dechlorination of 2,4,4′-trichlorobiphenyl (PCB 28) mediated by recombinant human CYP1A2
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Article
Open AccessTen years after: findings from the medical surveillance program on Health Effects in High-Level Exposure to PCB (HELPcB)
After the detection of high environmental and occupational exposure to polychlorinated biphenyls (PCBs) in a German recycling company for transformers and capacitors in 2010, the multidisciplinary medical surv...
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Open AccessThe human long noncoding RNAs CoroMarker, MALAT1, CDR1as, and LINC00460 in whole blood of individuals after controlled short-term exposure with ultrafine metal fume particles at workplace conditions, and in human macrophages in vitro
Short-term inhalation of occupationally relevant ultrafine zinc/copper (Zn/Cu) containing welding fumes has been shown to induce subclinical systemic inflammation, associated with an elevated risk for cardiova...
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Article
Open AccessThe pupillary light reflex (PLR) as a marker for the ability to work or drive – a feasibility study
The PLR (pupillary light reflex) can be a marker for pathological medical conditions, such as neurodegenerative or mental health disorders and diseases as well as marker for physiological alterations, such as ...
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Article
Open AccessHuman detection thresholds of DC, AC, and hybrid electric fields: a double-blind study
In the course of the ongoing transition of electric energy systems, transmission corridors are often upgraded to higher voltages and other technologies leading to another quality of human exposure. The study a...
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Article
Open AccessLongitudinal changes in telomere length in PCB-exposed individuals: interaction with CMV infection
We recently demonstrated a significant shortening of age-adapted telomere length (TL) in lymphocytes of polychlorinated biphenyls (PCB)-exposed individuals. Here, we analyzed TL in individuals of the same PCB-...
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Open AccessDoes stigmatization moderate the association between intention and implementation of learned prevention-strategies at work after a depressive episode? – a cross-sectional pilot study
A depressive episode is a frequent reason for production loss due to long periods of absence at work. To maintain work ability after depression, affected employees need to implement learned co** strategies f...
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Article
Open AccessAssociation of plasma PCB levels and HbA1c concentration in Iran
The rapid increase in prevalence of diabetes mellitus over the last decades warrants more attention to the effects of environmental and occupational exposures on glucose metabolism. Our study aimed to assess t...
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Article
Open AccessPolychlorinated biphenyls and depression: cross-sectional and longitudinal investigation of a dopamine-related Neurochemical path in the German HELPcB surveillance program
Exposure to polychlorinated biphenyls (PCBs) is associated with depressive symptomatology. A cause of depressive symptoms is a disturbance in the neurotransmitter system of dopamine (DA). Animal as well as hum...
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Open AccessMigrating pleural plaque in a patient with asbestos induced pleural disease: a case report
Health surveillance of formerly asbestos exposed individuals focus on early detection of asbestos related diseases, such as lung fibrosis (asbestosis), pleural plaques, mesothelioma and lung cancer in particul...
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Article
Open AccessBiological effects of exposure to static electric fields in humans and vertebrates: a systematic review
High-voltage direct current (HVDC) lines are the technology of choice for the transport of large amounts of energy over long distances. The operation of these lines produces static electric fields (EF), but th...
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Open AccessAccelerated telomere shortening in peripheral blood lymphocytes after occupational polychlorinated biphenyls exposure
Polychlorinated biphenyls (PCBs) are organochlorine pollutants with a worldwide dissemination. We examined telomere length (TL) in peripheral blood cells of 207 individuals with a high body burden of PCBs due ...
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Human biomonitoring of aluminium after a single, controlled manual metal arc inert gas welding process of an aluminium-containing worksheet in nonwelders
Several existing field studies evaluate aluminium welding works but no thoroughly controlled exposure scenario for welding fume has been described yet. This study provides information about the uptake and elim...
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Open AccessA technical support tool for joint range of motion determination in functional diagnostics - an inter-rater study
The examination of joint range of motion (RoM) is part of musculo-skeletal functional diagnostics, used, for example, in occupational examinations. Various examination methodologies exist that have been optimi...
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Article
Open AccessRadiological surveillance of formerly asbestos-exposed power industry workers: rates and risk factors of benign changes on chest X-ray and MDCT
To determine the prevalence of asbestos-related changes on chest X-ray (CXR) and low-dose multidetector-row CT (MDCT) of the thorax in a cohort of formerly asbestos-exposed power industry workers and to assess...
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Article
Open AccessIs it useful to combine sputum cytology and low-dose spiral computed tomography for early detection of lung cancer in formerly asbestos-exposed power industry workers?
Low-dose spiral computed tomography (LDSCT) in comparison to conventional chest X-ray proved to be a highly sensitive method of diagnosing early stage lung cancer. However, centrally located early stage lung t...
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Changes of mesothelin and osteopontin levels over time in formerly asbestos-exposed power industry workers
In patients develo** malignant pleural mesothelioma (MPM) or lung cancer, using effective tumour markers is the quickest way to ensure early diagnosis and improve survival time. The aim of our study was to a...
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Article
The incremental effect of psychosocial workplace factors on the development of neck and shoulder disorders: a systematic review of longitudinal studies
To systematically analyse evidence on the incremental effect of work-related psychosocial risk factors on the development of neck and shoulder disorders, as reported in longitudinal studies.
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Experimental exposure of healthy subjects with emissions from a gas metal arc welding process—part II: biomonitoring of chromium and nickel
The objective of this study was to investigate whether there is a relationship between the external exposure dose of chromium and nickel caused by a metal active gas welding process with a solid high-alloyed s...
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Longitudinal evidence for the association between work-related physical exposures and neck and/or shoulder complaints: a systematic review
Most existing reviews focus on evidence for the association between neck and/or shoulder complaints and physical exposures at the workplace gathered from cross-sectional studies. In comparison, this review sum...