20 Result(s)

Article

Retraction Note: Role of the P2X7 receptor in inflammation-mediated changes in the osteogenesis of periodontal ligament stem cells

**n-Yue Xu, **ao-Tao He, Jia Wang, Xuan Li, Yu **a, Yi-Zhou Tan… in Cell Death & Disease (2023)

Article

Roles of extracellular vesicles in periodontal homeostasis and their therapeutic potential

Periodontal tissue is a highly dynamic and frequently stimulated area where homeostasis is easily destroyed, leading to proinflammatory periodontal diseases. Bacteria–bacteria and cell–bacteria interactions pl...

Dao-Kun Deng, Jiu-Jiu Zhang, Dian Gan, Jie-Kang Zou… in Journal of Nanobiotechnology (2022)

Article

Correction: The proangiogenic effects of extracellular vesicles secreted by dental pulp stem cells derived from periodontally compromised teeth

Huan Zhou, Xuan Li, Yuan Yin, **ao-Tao He, Ying An… in Stem Cell Research & Therapy (2022)

Article

Metformin combats high glucose-induced damage to the osteogenic differentiation of human periodontal ligament stem cells via inhibition of the NPR3-mediated MAPK pathway

High glucose-induced damage to the osteogenic differentiation of human periodontal ligament stem cells (PDLSCs) has long been a challenge to periodontal regeneration for diabetic individuals. Metformin is an a...

Yi-Lin Zhang, Fen Liu, Zhi-Bang Li, **ao-Tao He, Xuan Li… in Stem Cell Research & Therapy (2022)

Article

LncRNA GACAT2 binds with protein PKM1/2 to regulate cell mitochondrial function and cementogenesis in an inflammatory environment

Periodontal ligament stem cells (PDLSCs) are a key cell type for restoring/regenerating lost/damaged periodontal tissues, including alveolar bone, periodontal ligament and root cementum, the latter of which is...

Xuan Li, Bei-Min Tian, Dao-Kun Deng, Fen Liu, Huan Zhou, De-Qin Kong… in Bone Research (2022)

Article

Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process

Stem cells that have undergone long-term ex vivo expansion are most likely functionally compromised (namely cellular senescence) in terms of their stem cell properties and therapeutic potential. Due to its abi...

Yi-Zhou Tan, **n-Yue Xu, Ji-Min Dai, Yuan Yin, **ao-Tao He… in Stem Cell Research & Therapy (2021)

Article

Suppression of histone deacetylases by SAHA relieves bone cancer pain in rats via inhibiting activation of glial cells in spinal dorsal horn and dorsal root ganglia

Robust activation of glial cells has been reported to occur particularly during the pathogenesis of bone cancer pain (BCP). Researchers from our group and others have shown that histone deacetylases (HDACs) pl...

**ao-Tao He, **ao-Fan Hu, Chao Zhu, Kai-**ang Zhou… in Journal of Neuroinflammation (2020)

Article

The proangiogenic effects of extracellular vesicles secreted by dental pulp stem cells derived from periodontally compromised teeth

Although dental pulp stem cells (DPSCs) isolated from periodontally compromised teeth (P-DPSCs) have been demonstrated to retain pluripotency and regenerative potential, their use as therapeutics remains large...

Huan Zhou, Xuan Li, Yuan Yin, **ao-Tao He, Ying An… in Stem Cell Research & Therapy (2020)

Article

RETRACTED ARTICLE: Role of the P2X7 receptor in inflammation-mediated changes in the osteogenesis of periodontal ligament stem cells

Accumulating evidence indicates that the pluripotency of periodontal ligament stem cells (PDLSCs) is compromised under inflammatory conditions; however, the underlying mechanisms remain largely unexplored. In ...

**n-Yue Xu, **ao-Tao He, Jia Wang, Xuan Li, Yu **a, Yi-Zhou Tan… in Cell Death & Disease (2019)

Article

Correction to: Treatment of periodontal intrabony defects using autologous periodontal ligament stem cells: a randomized clinical trial

The original article [1] contains a major error carried across the captions of Tables 1, 2, and 3. In each table caption, the data were expressed as “mean ± standard deviation (SD)”; unfortunately, the authors...

Fa-Ming Chen, Li-Na Gao, Bei-Min Tian, **-Yu Zhang… in Stem Cell Research & Therapy (2018)

Article

Exosomes secreted by stem cells from human exfoliated deciduous teeth contribute to functional recovery after traumatic brain injury by shifting microglia M1/M2 polarization in rats

Traumatic brain injury (TBI) is one of the major causes of mortality and disability for all ages worldwide. Mesenchymal stem cells (MSCs)-originated exosomes have provided therapeutic effects. However, as an i...

Ye Li, Yuan-Yuan Yang, Jia-Li Ren, Feng Xu, Fa-Ming Chen… in Stem Cell Research & Therapy (2017)

Article

Influences of age-related changes in mesenchymal stem cells on macrophages during in-vitro culture

Mesenchymal stem cells (MSCs) have been widely used in cytotherapy and tissue engineering due to their immunosuppressive ability and regenerative potential. Recently, the immunomodulatory influence of MSCs has...

Yuan Yin, Rui-**n Wu, **ao-Tao He, **n-Yue Xu, Jia Wang… in Stem Cell Research & Therapy (2017)

Article

The use of platelet-rich fibrin combined with periodontal ligament and jaw bone mesenchymal stem cell sheets for periodontal tissue engineering

Periodontal regeneration involves the restoration of at least three unique tissues: cementum, periodontal ligament tissue (PDL) and alveolar bone tissue. Here, we first isolated human PDL stem cells (PDLSCs) a...

Zhong-Shan Wang, Zhi-Hong Feng, Guo-Feng Wu, Shi-Zhu Bai, Yan Dong… in Scientific Reports (2016)

Article

Treatment of periodontal intrabony defects using autologous periodontal ligament stem cells: a randomized clinical trial

Periodontitis, which progressively destroys tooth-supporting structures, is one of the most widespread infectious diseases and the leading cause of tooth loss in adults. Evidence from preclinical trials and sm...

Fa-Ming Chen, Li-Na Gao, Bei-Min Tian, **-Yu Zhang… in Stem Cell Research & Therapy (2016)

Article

Mesenchymal stem cells inhibit multiple myeloma cells via the Fas/Fas ligand pathway

Cell-based therapy represents a new frontier in the treatment of a wide variety of human diseases traditionally associated with morbidity outcomes, including those involving inflammation, autoimmunity, tissue ...

Ikiru Atsuta, Shiyu Liu, Yasuo Miura, Kentaro Akiyama… in Stem Cell Research & Therapy (2013)

Article

Composite glycidyl methacrylated dextran (Dex-GMA)/gelatin nanoparticles for localized protein delivery

Localized delivery of growth factors has significant potential as a future therapeutic strategy in tissue engineering and regenerative medicine. A nanoparticle vehicle was created and evaluated in this study w...

Fa-ming Chen, Zhi-wei Ma, Guang-ying Dong, Zhi-fen Wu in Acta Pharmacologica Sinica (2009)

Article

Preparation of recombinant human bone morphogenetic protein-2 loaded dextran-based microspheres and their characteristics

To prepare new pharmaceutical forms with sustained delivery properties of recombinant human bone morphogenetic protein-2 (rhBMP₂) for tissue engineering and guided tissue regeneration (GTR) use.

Fa-ming Chen, Zhi-fen Wu, Qin-tao Wang, Hong Wu… in Acta Pharmacologica Sinica (2005)