20 Result(s)
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Open AccessUnraveling the genome of Bacillus velezensis MEP218, a strain producing fengycin homologs with broad antibacterial activity: comprehensive comparative genome analysis
Bacillus sp. MEP218, a soil bacterium with high potential as a source of bioactive molecules, produces mostly C16–C17 fengycin and other cyclic lipopeptides (CLP) when growing under previously optimized culture c...
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Open AccessDiversity of gene expression responses to light quality in barley
Light quality influence on barley development is poorly understood. We exposed three barley genotypes with either sensitive or insensitive response to two light sources producing different light spectra, fluor...
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Open AccessGET_PANGENES: calling pangenes from plant genome alignments confirms presence-absence variation
Crop pangenomes made from individual cultivar assemblies promise easy access to conserved genes, but genome content variability and inconsistent identifiers hamper their exploration. To address this, we define...
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Open AccessGradual polyploid genome evolution revealed by pan-genomic analysis of Brachypodium hybridum and its diploid progenitors
Our understanding of polyploid genome evolution is constrained because we cannot know the exact founders of a particular polyploid. To differentiate between founder effects and post polyploidization evolution,...
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Open AccessFine-tuning of the flowering time control in winter barley: the importance of HvOS2 and HvVRN2 in non-inductive conditions
In winter barley plants, vernalization and photoperiod cues have to be integrated to promote flowering. Plant development and expression of different flowering promoter (HvVRN1, HvCO2, PPD-H1, HvFT1, HvFT3) and r...
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Article
Resequencing theVrs1 gene in Spanish barley landraces revealed reversion of six-rowed to two-rowed spike
Six-rowed spike 1 (Vrs1) is a gene of major importance for barley breeding and germplasm management as it is the main gene determining spike row-type (2-rowed vs. 6-rowed). This is a widely used DUS trait, and ha...
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Open AccessExtensive gene content variation in the Brachypodium distachyon pan-genome correlates with population structure
While prokaryotic pan-genomes have been shown to contain many more genes than any individual organism, the prevalence and functional significance of differentially present genes in eukaryotes remains poorly un...
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Article
BARLEYMAP: physical and genetic map** of nucleotide sequences and annotation of surrounding loci in barley
The BARLEYMAP pipeline was designed to map both genomic sequences and transcripts against sequence-enriched genetic/physical frameworks, with plant breeders as the main target users. It reports the most proba...
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Article
Selection footprints in barley breeding lines detected by combining genoty**-by-sequencing with reference genome information
This study is a retrospective analysis of an elite cross from the Spanish National Barley Breeding Program. This was the most successful cross produced in the breeding program in the past 20 years. The progeny...
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Article
Loss of neuronal 3D chromatin organization causes transcriptional and behavioural deficits related to serotonergic dysfunction
The interior of the neuronal cell nucleus is a highly organized three-dimensional (3D) structure where regions of the genome that are linearly millions of bases apart establish sub-structures with specialized ...
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Open AccessIntegrating bioinformatic resources to predict transcription factors interacting with cis-sequences conserved in co-regulated genes
Using motif detection programs it is fairly straightforward to identify conserved cis-sequences in promoters of co-regulated genes. In contrast, the identification of the transcription factors (TFs) interacting w...
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Article
Fine map** of the Rrs1 resistance locus against scald in two large populations derived from Spanish barley landraces
In two Spanish barley landraces with outstanding resistance to scald, the Rrs1 Rh4 locus was fine ...
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Article
Open AccessGenetic recombination is associated with intrinsic disorder in plant proteomes
Intrinsically disordered proteins, found in all living organisms, are essential for basic cellular functions and complement the function of ordered proteins. It has been shown that protein disorder is linked t...
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Article
OsRMC, a negative regulator of salt stress response in rice, is regulated by two AP2/ERF transcription factors
High salinity causes remarkable losses in rice productivity worldwide mainly because it inhibits growth and reduces grain yield. To cope with environmental changes, plants evolved several adaptive mechanisms, ...
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Open AccessProtein disorder in plants: a view from the chloroplast
The intrinsically unstructured state of some proteins, observed in all living organisms, is essential for basic cellular functions. In this field the available information from plants is limited but it has bee...
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HvFT1 (VrnH3) drives latitudinal adaptation in Spanish barleys
In barley, three genes are responsible for the vernalization requirement: VrnH1, VrnH2 and VrnH3. The winter growth habit of barley requires the presence of a recessive VrnH1 allele, together with an active VrnH2
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Article
Open AccessEvolutionary divergence of chloroplast FAD synthetase proteins
Flavin adenine dinucleotide synthetases (FADSs) - a group of bifunctional enzymes that carry out the dual functions of riboflavin phosphorylation to produce flavin mononucleotide (FMN) and its subsequent adeny...
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Open AccessPrediction of TF target sites based on atomistic models of protein-DNA complexes
The specific recognition of genomic cis-regulatory elements by transcription factors (TFs) plays an essential role in the regulation of coordinated gene expression. Studying the mechanisms determining binding spe...
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OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer
Epithelial ovarian cancer (EOC), the leading cause of death from gynecological malignancy, is a poorly understood disease. The typically advanced presentation of EOC with loco-regional dissemination in the per...
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Crystal: clear difference from glass
