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Article
Cinematic volume rendering algorithm based on multiple lights photon map**
Cinematic volume rendering, which can obtain highly realistic rendering results, is considered to be the next-generation volume rendering technology. Cinematic volume rendering generally uses ray tracing algor...
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Article
Open AccessAssociation between ambient particulate matters and anhedonia among patients with depression
Recent studies have linked ambient air pollution to depression. Anhedonia is a core symptom of depression which severely impacts on prognosis. The present study aims to investigate the association of PM2.5 and...
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Article
Open AccessElectrochemical Activity of Carbon-Supported Pt-Nanoparticles: Effect of Pt-Precursor Ligand and/or Presence of Anions During Polyol Synthesis
This study revisits the impacts of the presence of OH− and Cl− anions and/or different forms of Pt precursors during polyol synthesis of carbon-supported electrocatalysts. Efficiency of the synthesis process in t...
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Article
Open AccessAn evolved pyrrolysyl-tRNA synthetase with polysubstrate specificity expands the toolbox for engineering enzymes with incorporation of noncanonical amino acids
Aminoacyl-tRNA synthetase (aaRS) is a core component for genetic code expansion (GCE), a powerful technique that enables the incorporation of noncanonical amino acids (ncAAs) into a protein. The aaRS with poly...
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Article
CCDC146 is required for sperm flagellum biogenesis and male fertility in mice
Multiple morphological abnormalities of the flagella (MMAF) is a severe disease of male infertility, while the pathogenetic mechanisms of MMAF are still incompletely understood. Previously, we found that the d...
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Article
Gene–environment interaction analysis under the Cox model
For the survival of cancer and many other complex diseases, gene–environment (G-E) interactions have been established as having essential importance. G-E interaction analysis can be roughly classified as margi...
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Article
Open AccessAuthor Correction: Sustained antidepressant effect of ketamine through NMDAR trap** in the LHb
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Article
Open AccessSustained antidepressant effect of ketamine through NMDAR trap** in the LHb
Ketamine, an N-methyl-d-aspartate receptor (NMDAR) antagonist1, has revolutionized the treatment of depression because of its potent, rapid and sustained antidepressant effects2–4. Although the elimination half-l...
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Article
Nuclear smooth muscle α-actin participates in vascular smooth muscle cell differentiation
Missense variants throughout ACTA2, encoding α-smooth muscle actin (αSMA), predispose to adult-onset thoracic aortic disease, but variants disrupting arginine 179 (R179) lead to smooth muscle dysfunction syndrome...
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Article
Effects of natural forest conversion and plantation tree species composition on soil macrofauna communities in Northeast China mountains
As primary and secondary forests are being replaced by plantations across the globe, the soil macrofauna community structure is also affected, but little is known about the impact of mixed culture plantations ...
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Article
Record-breaking pre-flood rainfall over South China in 2022: role of historic warming over the Northeast Pacific and Maritime Continent
In 2022, South China suffered severe flooding due to unexpected persistent heavy rainfall in the pre-flood season. The in situ cumulative precipitation amount during May–June in South China broke the record es...
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Article
Open AccessZINBMM: a general mixture model for simultaneous clustering and gene selection using single-cell transcriptomic data
Clustering is a critical component of single-cell RNA sequencing (scRNA-seq) data analysis and can help reveal cell types and infer cell lineages. Despite considerable successes, there are few methods tailored...
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Article
3D vessel extraction using a scale-adaptive hybrid parametric tracker
3D vessel extraction has great significance in the diagnosis of vascular diseases. However, accurate extraction of vessels from computed tomography angiography (CTA) data is challenging. For one thing, vessels...
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Article
Temporal and spatial changes of water quality in intensively developed urban rivers and water environment improvement: a case study of the Longgang River in Shenzhen, China
The water quality status, spatial and temporal change processes, and water environment improvement process of urban rivers are valuable lessons to be learned under the sustainable development strategy. This st...
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Article
Open AccessR-loop-dependent promoter-proximal termination ensures genome stability
The proper regulation of transcription is essential for maintaining genome integrity and executing other downstream cellular functions1,2. Here we identify a stable association between the genome-stability regula...
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Article
Studies of Thermo-electromagnetics Mechanisms Regulating a Direct/Hybrid Microwave Sintering of α and β-Aluminum Oxide: Kinetics of Densification and Influence of Magnetic Field
Most existing studies present microwaves as a heating technique that improves alumina sintering. However, the experimental device limits have hampered the identification of the effects’ nature. Because of this...
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Article
Open AccessA multifunctional ‘golden cicada’ nanoplatform breaks the thermoresistance barrier to launch cascade augmented synergistic effects of photothermal/gene therapy
Photothermal therapy (PTT) is taken as a promising strategy for cancer therapy, however, its applicability is hampered by cellular thermoresistance of heat shock response and insufficient accumulation of photo...
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Article
Open AccessThe mediating role of inflammation in the association between pregnancy loss history and gestational diabetes mellitus
To assess the association of pregnancy loss history with an elevated risk of Gestational diabetes mellitus (GDM) and to investigate whether this association was mediated by high-sensitivity C-reactive protein ...
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Article
Structural Origins for Enhanced Thermal Stability and Glass-Forming Ability of Co–B Metallic Glasses with Y and Nb Addition
The effects of Y and Nb addition on thermal stability, glass-forming ability (GFA), and magnetic softness of Co75B25 metallic glass (MG) were comprehensively investigated. The experimental results indicated that ...
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Article
Extreme Cold Events in North America and Eurasia in November-December 2022: A Potential Vorticity Gradient Perspective
From 17 November to 27 December 2022, extremely cold snowstorms frequently swept across North America and Eurasia. Diagnostic analysis reveals that these extreme cold events were closely related to the establi...
