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    Nuclear smooth muscle α-actin participates in vascular smooth muscle cell differentiation

    Missense variants throughout ACTA2, encoding α-smooth muscle actin (αSMA), predispose to adult-onset thoracic aortic disease, but variants disrupting arginine 179 (R179) lead to smooth muscle dysfunction syndrome...

    Callie S. Kwartler, Albert J. Pedroza, Anita Kaw… in Nature Cardiovascular Research (2023)