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1,159 Result(s)
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Article
Open AccessEnhancing angiogenesis and inhibiting apoptosis: evaluating the therapeutic efficacy of bone marrow mesenchymal stem cell-derived exosomes in a DHEA-induced PCOS mouse model
Polycystic Ovary Syndrome (PCOS) is a widespread endocrine disorder among women, characterized by symptoms like ovarian cysts, hormonal imbalance, and metabolic issues. This research evaluates the therapeutic ...
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Open AccessPlant height as an indicator for alpine carbon sequestration and ecosystem response to warming
Growing evidence indicates that plant community structure and traits have changed under climate warming, especially in cold or high-elevation regions. However, the impact of these warming-induced changes on ec...
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Open AccessHarnessing instability for work hardening in multi-principal element alloys
The strength–ductility trade-off has long been a Gordian knot in conventional metallic structural materials and it is no exception in multi-principal element alloys. In particular, at ultrahigh yield strengths...
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Open AccessSome remarks about deformation theory and formality conjecture
Using the algebraic criterion proved by Bandiera, Manetti and Meazzini, we show the formality conjecture for universally gluable objects with linearly reductive automorphism groups in the bounded derived categ...
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Open AccessEffect of LncRNA LOC106505926 on myogenesis and Lipogenesis of porcine primary cells
Skeletal muscle development and fat deposition have important effects on meat quality. The study of regulating skeletal muscle development and fat deposition is of great significance in improving the quality o...
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Open AccessOptimizing sparse general matrix–matrix multiplication for DCUs
Sparse general matrix–matrix multiplication (SpGEMM) is a crucial and complex computational task in many practical applications. Improving the performance of SpGEMM on SIMT processors like modern GPUs is chall...
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Open AccessPrognostic impact and immunotherapeutic implications of NETosis-related prognostic model in clear cell renal cell carcinoma
The ramifications of necroptosis on the prognostication of clear cell renal cell carcinoma (ccRCC) remain inadequately expounded.
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Open AccessRelationship between obstructive sleep apnoea syndrome and gastrointestinal diseases: a systematic review and Meta-analysis
Studies exploring the association between obstructive sleep apnoea syndrome (OSA) and gastrointestinal diseases (GID) are important for enhancing clinical outcomes. This study aimed to systematically assess th...
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Open AccessHead model dataset for mixed reality navigation in neurosurgical interventions for intracranial lesions
Mixed reality navigation (MRN) technology is emerging as an increasingly significant and interesting topic in neurosurgery. MRN enables neurosurgeons to “see through” the head with an interactive, hybrid visua...
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Open AccessExosomes derived from adipose tissue-derived stem cells alleviated H2O2-induced oxidative stress and endothelial-to-mesenchymal transition in human umbilical vein endothelial cells by inhibition of the mir-486-3p/Sirt6/Smad signaling pathway
Hypertrophic scar (HS) is characterized by excessive collagen deposition and myofibroblasts activation. Endothelial-to-mesenchymal transition (EndoMT) and oxidative stress were pivotal in skin fibrosis process...
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Open AccessMutant kri1l causes abnormal retinal development via cell cycle arrest and apoptosis induction
Damage to the ribosome or an imbalance in protein biosynthesis can lead to some human diseases, such as diabetic retinopathy (DR) and other eye diseases. Here, we reported that the kri1l gene was responsible for ...
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Open AccessIn vivo rescue of genetic dilated cardiomyopathy by systemic delivery of nexilin
Dilated cardiomyopathy (DCM) is one of the most common causes of heart failure. Multiple identified mutations in nexilin (NEXN) have been suggested to be linked with severe DCM. However, the exact association ...
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Open AccessGouqi-derived nanovesicles (GqDNVs) inhibited dexamethasone-induced muscle atrophy associating with AMPK/SIRT1/PGC1α signaling pathway
With the increasing trend of global aging, sarcopenia has become a significant public health issue. Goji berry, also known as “Gou qi zi” in China, is a traditional Chinese herb that can enhance the structure ...
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Open AccessMedium-cumulative dose of cytarabine in consolidation therapy shows the greatest benefit in AML patients
High-dose cytarabine (HDAC) is commonly used for consolidation therapy in young acute myeloid leukemia (AML) patients, but the dosage of cytarabine is still controversial in the clinic due to its obvious post-...
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Open AccessDeep Visual-guided and Deep Reinforcement Learning Algorithm Based for Multip-Peg-in-Hole Assembly Task of Power Distribution Live-line Operation Robot
The inspection and maintenance of power distribution network are crucial for efficiently delivering electricity to consumers. Due to the high voltage of power distribution network lines, manual live-line opera...
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Open AccessA multi-view fusion lightweight network for CRSwNPs prediction on CT images
Accurate preoperative differentiation of the chronic rhinosinusitis (CRS) endotype between eosinophilic CRS (eCRS) and non-eosinophilic CRS (non-eCRS) is an important topic in predicting postoperative outcomes...
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Open AccessAssociation between social capital and utilization of essential public health services among elderly migrants: a multilevel logistic study based on the 2017 China migrant dynamic survey (CMDS)
As the number of elderly migrants in China continues to grow, it is necessary to pay closer attention to their health and health services. Some studies have confirmed that social capital plays a significant ro...
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Open AccessThe NTE domain of PTENα/β promotes cancer progression by interacting with WDR5 via its SSSRRSS motif
PTENα/β, two variants of PTEN, play a key role in promoting tumor growth by interacting with WDR5 through their N-terminal extensions (NTEs). This interaction facilitates the recruitment of the SET1/MLL methyl...
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Open AccessRetraction Note: Research on reliability evolutionary optimization of relays device based on Multi-Markov model
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Open AccessEffect of plant-soil system on the restoration of community stability after wildfire in the northeast margin of Qinghai-Tibet plateau
Wildfires, as an environmental filter, are pivotal ecological disturbances that reshape plant communities and soil dynamics, playing a crucial role in regulating biogeographic patterns and ecosystem services. ...