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Transcriptomics profiling reveal the heterogeneity of white and brown adipocyte
The marker genes associated with white adipocytes and brown adipocytes have been previously identified; however, these markers have not been updated...
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Facile adipocyte uptake and liver/adipose tissue delivery of conjugated linoleic acid-loaded tocol nanocarriers for a synergistic anti-adipogenesis effect
Obesity is a major risk to human health. Adipogenesis is blocked by α-tocopherol and conjugated linoleic acid (CLA). However, their effect at...
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Effect of Single Clove Black Garlic Extract on Lipid Accumulation During Adipocyte Differentiation Using 3T3-L1 Cell Line
Obesity, defined as an excessive adipose tissue mass, is a major factor in increasing the risk of serious diseases such as heart disease,...
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Metformin booster adipocyte-targeted gene therapy for the treatment of obesity and related metabolic syndromes
Obesity has become an important public problem that endangers human conditions and urgently needs to be solved. However, most weight-loss drugs on...
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Nootkatone (NK), a grapefruit-derived aromatic compound, inhibited lipid accumulation by regulating JAK2-STAT signaling and antioxidant response in adipocyte
Nootkatone (NK) is an aromatic compound derived from grapefruit. This study aimed to investigate the inhibitory effect of NK on lipid accumulation...
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Asimina triloba (pawpaw) fruit extract suppresses adipocyte differentiation and lipogenesis-related protein expression in 3T3-L1 cells
Obesity is a health condition accompanied by life-threatening comorbidities; hence, there is an increasing need for anti-obesity agents. The...
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Schisandra chinensis-derived gomisin C suppreses lipid accumulation by JAK2-STAT signaling in adipocyte
Gomisin C is a lignan isolated from the fruit of S chisandra chinensis . The current study aimed to investigate the effect of gomisin C on lipid...
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Inhibition of 3T3-L1 Adipocyte Differentiation by D-allulose
Obesity is a serious problem in modern society and its prevalence continues to increase worldwide, resulting in metabolic disorder related diseases....
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Fluorescent Genetic Tools for Studying Brown Fat Development and Function in Mice
Techniques to trace and isolate brown adipocyte precursor and adipocytes during development and disease are essential to fully understand brown...
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Effects of caffeoylquinic acid analogs derived from aerial parts of Artemisia iwayomogi on adipogenesis
Artemisia iwayomogi (AI) is a perennial herb found in Korea. Its ground parts are dried and used in food and traditional medicine for treating...
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The Effect of Methanolic Valeriana officinalis Root Extract on Adipocyte Differentiation and Adiponectin Production in 3T3-L1 Adipocytes
Adipose tissue is an endocrine organ and its endocrine function is closely associated with type 2 diabetes mellitus. Valeriana officinalis (Valerian)...
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Centella asiatica lowers body fat accumulation via regulating cholesterol homeostasis- and lipid metabolism-related genes in mice with high-fat, high-sugar diet-induced obesity
To understand the mechanisms involved in the anti-obesity effects Centella asiatica (CA), we examined body weight, serum levels, white adipose tissue...
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A review of the role of liposome-encapsulated phytochemicals targeting PPAR Ɣ and associated pathways to combat obesity
A limited number of studies have directly examined the effects of liposomal encapsulated phytochemicals and their anti-obesity effects in adults....
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Antioxidant and anti-obesity effects of in vitro digesta of germinated buckwheat
Buckwheat germinated on days of 3, 5, and 7 was digested in vitro, and the antioxidant and anti-obesity effects of the digesta were evaluated. In...
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Analysis of Enhancers and Transcriptional Networks in Thermogenic Adipocytes
Transcription factor (TF) networks orchestrate the regulation of gene programs in mammalian cells, including white and brown adipocytes. In this...
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Dibenzoylmethane ameliorates adiposity-mediated neuroinflammatory response and inflammation-mediated neuronal cell death in mouse microglia and neuronal cells
Dibenzoylmethane (DBM), a licorice-derived component, has numerous health benefits. The current study aimed to investigate the effect of DBM on...
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Effect of traditional herbal medicine, danggui-yukhwang-tang, on post-menopausal weight gain in ovariectomized high-fat diet rats
The decrease in estrogen due to menopause leads to impaired lipid metabolism and is closely related to the increase in metabolic syndrome due to...
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Evaluation of antioxidant and anti-obesity potential of Sargassum extracts
Sargassum are brown algae belonging to the class Phaeophyceae . Brown algae are rich in nutrients and widely used in food. Most previous experiments...
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Sodium-potassium Adenosine Triphosphatase α2 Subunit (ATP1A2) Negatively Regulates UCP1-dependent and UCP1-independent Thermogenesis in 3T3-L1 Adipocytes
Increasing the number of brite cells (browning) in white adipocytes has attracted considerable attention to combat obesity because brite cells also...
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1,3,5,8-Tetrahydroxyxanthone suppressed adipogenesis via activating Hedgehog signaling in 3T3-L1 adipocytes
In this study, we investigated the effect of 1,3,5,8-tetrahydroxyxanthone (THX) on the adipogenesis of 3T3-L1 adipocytes. THX, a xanthone isolated...
