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MED-YOLOv8s: a new real-time road crack, pothole, and patch detection model
Real-time road damage detection and assessment is crucial to ensure road safety. Traditional road damage detection methods mostly rely on manual labor, which is not only inefficient, but it is also difficult t...
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Article
Open AccessLipid peroxidation in osteoarthritis: focusing on 4-hydroxynonenal, malondialdehyde, and ferroptosis
Osteoarthritis (OA) is a multifactorial and increasingly prevalent degenerative disease that affects the whole joint. The pathogenesis of OA is poorly understood and there is a lack of therapeutic intervention...
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Article
Open AccessInhibition of TRADD ameliorates chondrocyte necroptosis and osteoarthritis by blocking RIPK1-TAK1 pathway and restoring autophagy
Osteoarthritis (OA) is an age-related disease characterized by cartilage degeneration. TNFR1-associated death domain protein (TRADD) is a key upstream molecule of TNF-α signals but its role in OA pathogenesis ...
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Article
Open AccessDesign and experiment of a combined peeling machine for water chestnut
Water chestnut is a characteristic aquatic vegetable in China, and its demand for peeling fresh fruit is increasing rapidly. Aiming at the existing problems of high labor intensity and low efficiency of manual...
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Article
Open AccessPERK controls bone homeostasis through the regulation of osteoclast differentiation and function
Osteoclasts are multinucleated giant cells with the ability to degrade bone tissue, and are closely related to abnormal bone metabolic diseases. Endoplasmic reticulum (ER) is an organelle responsible for prote...
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Article
Loss of heterozygosity by SCRaMbLEing
Genetic variation drives phenotypic evolution within populations. Genetic variation can be divided into different forms according to the size of genomic changes. However, study of large-scale genomic variation...
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Article
Spatial patterns and driving forces of land change in Tibetan-inhabited Three Rivers Headwaters region, China
The Three Rivers Headwaters Region (TRHR) plays a key role in regulating water supply and climate of East Asia. A comprehensive understanding of the processes and driving forces of the long-term land use dynam...
