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  1. Article

    Open Access

    Lipid peroxidation in osteoarthritis: focusing on 4-hydroxynonenal, malondialdehyde, and ferroptosis

    Osteoarthritis (OA) is a multifactorial and increasingly prevalent degenerative disease that affects the whole joint. The pathogenesis of OA is poorly understood and there is a lack of therapeutic intervention...

    **ong Zhang, Liangcai Hou, Zhou Guo, Genchun Wang, **gting Xu… in Cell Death Discovery (2023)

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  2. Article

    Open Access

    Inhibition of TRADD ameliorates chondrocyte necroptosis and osteoarthritis by blocking RIPK1-TAK1 pathway and restoring autophagy

    Osteoarthritis (OA) is an age-related disease characterized by cartilage degeneration. TNFR1-associated death domain protein (TRADD) is a key upstream molecule of TNF-α signals but its role in OA pathogenesis ...

    Kai Sun, Zhou Guo, **ming Zhang, Liangcai Hou, Shuang Liang… in Cell Death Discovery (2023)

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