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Article
DC-CLM, a cadherin-like molecule cloned from human dendritic cells, inhibits growth of breast cancer cells
To identify the characteristics and function of a cadherin-like molecule, cloned from a human dendritic cell (DC) cDNA library and designated DC-derived cadherin-like molecule (DC-CLM).
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Article
Apoptotic cell administration enhances pancreatic islet engraftment by induction of regulatory T cells and tolerogenic dendritic cells
Apoptotic cell transfer has been found to be able to facilitate engraftment of allograft. However, the underlying mechanisms remain to be fully understood. Here we demonstrate that intravenous administration o...
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Article
Tumor-educated B cells selectively promote breast cancer lymph node metastasis by HSPA4-targeting IgG
Primary tumors may create the premetastatic niche in secondary organs for subsequent metastasis. Humoral immunity contributes to the progression of certain cancers, but the roles of B cells and their derived a...
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Chapter and Conference Paper
MOOC Vocal Music Blended Teaching Mode and Digital Resource Platform Design in the Information Age
Due to the application of computer technology and network technology, the learning speed is getting faster and faster. From the era of digital processing to microcomputers, then to networking, blended teaching...
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Article
Open AccessEpigenetic silencing and tumor suppressor gene of HAND2 by targeting ERK signaling in colorectal cancer
The screening biomarkers for early detection of colorectal cancer (CRC) is lacking. The aim is to identify epigenetic silenced genes and clarify its roles and underlying mechanism in CRC. We conducted integrat...
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Article
Open AccessCorrection: Epigenetic silencing and tumor suppressor gene of HAND2 by targeting ERK signaling in colorectal cancer
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Article
ADAMTS10 inhibits aggressiveness via JAK/STAT/c-MYC pathway and reprograms macrophage to create an anti-malignant microenvironment in gastric cancer
A disintegrin and metalloproteinase with thrombospondin motifs 10 (ADAMTS10) plays a role in extracellular matrix and correlates with Weill–Marchesani syndrome. However, its role in gastric cancer remains unkn...
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Article
Open AccessLAD1 promotes malignant progression by diminishing ubiquitin-dependent degradation of vimentin in gastric cancer
Ladinin-1 (LAD1), an anchoring filament protein, has been associated with several cancer types, including cancers of the colon, lungs, and breast. However, it is still unclear how and why LAD1 causes gastric c...
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Article
Open AccessIntercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis
Gastric cancer (GC) is a fatal cancer with unclear pathogenesis. In this study, we explored the function and potential mechanisms of intercellular adhesion molecule 2 (ICAM2) in the development and advancement...
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Article
Open AccessTargeting RPA promotes autophagic flux and the antitumor response to radiation in nasopharyngeal carcinoma
Autophagy is involved in nasopharyngeal carcinoma (NPC) radioresistance. Replication protein A 1 (RPA1) and RPA3, substrates of the RPA complex, are potential therapeutic targets for reversing NPC radioresista...
