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  1. Article

    Open Access

    Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis

    Gastric cancer (GC) is a fatal cancer with unclear pathogenesis. In this study, we explored the function and potential mechanisms of intercellular adhesion molecule 2 (ICAM2) in the development and advancement...

    **aocheng Tang, **tuan Huang, Yingming Jiang, Jun Qiu… in Journal of Translational Medicine (2023)

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  2. Article

    Open Access

    LAD1 promotes malignant progression by diminishing ubiquitin-dependent degradation of vimentin in gastric cancer

    Ladinin-1 (LAD1), an anchoring filament protein, has been associated with several cancer types, including cancers of the colon, lungs, and breast. However, it is still unclear how and why LAD1 causes gastric c...

    Yingming Jiang, Yanchun Feng, **tuan Huang… in Journal of Translational Medicine (2023)

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  3. Article

    ADAMTS10 inhibits aggressiveness via JAK/STAT/c-MYC pathway and reprograms macrophage to create an anti-malignant microenvironment in gastric cancer

    A disintegrin and metalloproteinase with thrombospondin motifs 10 (ADAMTS10) plays a role in extracellular matrix and correlates with Weill–Marchesani syndrome. However, its role in gastric cancer remains unkn...

    Junyi Zhou, Tuoyang Li, Hao Chen, Yingming Jiang, Yandong Zhao… in Gastric Cancer (2022)

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