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  1. No Access

    Article

    Road feature enhancement network for remote sensing images based on DeepLabV3Plus

    Extracting road information from complex high-resolution remote sensing images to update road networks has become a focus research field in recent years. However, the scale of roads in remote sensing images va...

    Liang Dong, Enci Zhu, Lei Zhu, Quanxing Wang… in Signal, Image and Video Processing (2024)

  2. Article

    Open Access

    Sirtinol regulates the balance of Th17/Treg to prevent allograft rejection

    Current immunosuppressive medications used after transplantation induce significant toxicity , and a new medication regimen is needed. Based on recent research, Sirt1 exerts a proinflammatory effect on the imm...

    Qing Ye, Mingjian Zhang, Yang Wang, Shangxi Fu, Shu Han, Liming Wang… in Cell & Bioscience (2017)

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  3. No Access

    Article

    Apoptotic cell administration enhances pancreatic islet engraftment by induction of regulatory T cells and tolerogenic dendritic cells

    Apoptotic cell transfer has been found to be able to facilitate engraftment of allograft. However, the underlying mechanisms remain to be fully understood. Here we demonstrate that intravenous administration o...

    Cong Wu, Yi Zhang, Yingming Jiang, Quanxing Wang… in Cellular & Molecular Immunology (2013)

  4. No Access

    Article

    MicroRNA-185 suppresses proliferation, invasion, migration, and tumorigenicity of human prostate cancer cells through targeting androgen receptor

    Previous studies have shown that androgen receptor (AR) is involved in the progression of prostate cancer (CaP) by several mechanisms. However, how AR is regulated has not been fully understood. In this study,...

    Fajun Qu, **ngang Cui, Yi Hong, Junkai Wang, Yao Li… in Molecular and Cellular Biochemistry (2013)

  5. Article

    Open Access

    Flurbiprofen, a Cyclooxygenase Inhibitor, Protects Mice from Hepatic Ischemia/Reperfusion Injury by Inhibiting GSK-3β Signaling and Mitochondrial Permeability Transition

    Flurbiprofen acts as a nonselective inhibitor for cyclooxygenases (COX-1 and COX-2), but its impact on hepatic ischemia/reperfusion (I/R) injury remains unclear. Mice were randomized into sham, I/R and flurbip...

    Hailong Fu, Huan Chen, Chengcai Wang, Haitao Xu, Fang Liu, Meng Guo… in Molecular Medicine (2012)

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  6. No Access

    Article

    Dendritic Cells Transduced with SOCS1 Gene Exhibit Regulatory DC Properties and Prolong Allograft Survival

    SOCS1 is a key regulator of cytokine signaling and is important for maintaining balance in the immune system. It is thought to participate in negative feedback loops in cytokine signaling and may be an importa...

    Hong Fu, Shaohua Song, Fang Liu, Zhijia Ni, Yi Tang… in Cellular & Molecular Immunology (2009)

  7. No Access

    Article

    Effective induction of immune tolerance by portal venous infusion with IL-10 gene-modified immature dendritic cells leading to prolongation of allograft survival

    Dendritic cells (DC) not only initiate T cell responses, but are also involved in the induction of tolerance. The functional properties of DC are strictly dependent on their state of maturation. It has been sh...

    Ming Zhang, Quanxing Wang, Yushan Liu, Yan** Sun… in Journal of Molecular Medicine (2004)

  8. No Access

    Article

    TGF-β1 gene modified immature dendritic cells exhibit enhanced tolerogenicity but induce allograft fibrosis in vivo

    Administration of donor-derived immature dendritic cells (DC) can prolong the survival of MHC-mismatched cardiac allografts. Genetic modification of DC by immunosuppressive molecules can enhance their potentia...

    Wenji Sun, Quanxing Wang, Lihuang Zhang, Jian** Pan… in Journal of Molecular Medicine (2002)

  9. No Access

    Article

    The therapeutic effect of intratumoral injection of GM-CSF gene-modified allogenic macrophages on tumor-bearing mice

    Both the antigen presenting ability and the cytotoxicity of macrophages can be enhanced by GM-CSF gene transfer. In the present study, the therapeutic effect of intratumoral injection with GM-CSF gene-modified...

    Yizhi Yu, Xuetao Cao, Hong Lei, Quanxing Wang… in Chinese Journal of Cancer Research (1998)

  10. No Access

    Article

    Antitumor effect of intratumoral injection of liposome-encapsulated G-CSF gene andin situ biological characteristics of the treated tumor cells

    In order to investigate the antitumor effects of thein vivo G-CSF gene therapy mediated by liposome and its mechanisms, human G-CSF gene was encapsulated into liposome and was directly injected into tumor mass of...

    Yan** Sun, Xuetao Cao, Quanxing Wang, Yuanhe Wang… in Chinese Journal of Cancer Research (1998)

  11. No Access

    Article

    Immunological characteristics of the leukemia cells transfected with oncostatin M gene by recombinant adenovieus

    In the present study, FBL-3 murine erythroleukemia cells were transacted with human OSM(hOSM) gene by recombinant adenovirus, then the immunological properties of hOSM gene-transfected FBL-3 cells(FBL-3-OSM+) wer...

    Quanxing Wang, Xuetao Cao, **g Mi, Wei** Zhang in Chinese Journal of Cancer Research (1997)

  12. No Access

    Article

    Mössbauer studies of hemoglobin of the patients with liver cancer and cirrhosis

    Red blood cells (RBC) of the patients with primary liver cancer and with cirrhosis were investigated by using Mössbauer spectroscopy. Control measurements were carried out on RBC from normal adults. The Mössba...

    **nlei Ni, Yuanfu Hsia, Rongchuan Liu, Qingyou Lu, Runsheng Huang… in Hyperfine Interactions (1992)