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Article
Activating MC4R Promotes Functional Recovery by Repressing Oxidative Stress-Mediated AIM2 Activation Post-spinal Cord Injury
Spinal cord injury (SCI) is a destructive neurological trauma that induces permanent sensory and motor impairment as well as a deficit in autonomic physiological function. Melanocortin receptor 4 (MC4R) is a G...
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Article
Characteristics and Formation Mechanism of Ca–Mg–Al–Si–O + (Ca,Mn)S Duplex Inclusions in Ca–S Free-Cutting Steel
Large numbers of long strip-shaped pure MnS inclusions in steel will result in anisotropy of mechanical properties. To obtain more duplex (Ca,Mn)S inclusions in steel through adding Ca can decrease the proport...
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Article
Open AccessBi-directional context-aware network for the nested named entity recognition
The Span-based model can effectively capture the complex entity structure in the text, thus becoming the mainstream model for nested named entity recognition (Nested NER) tasks. However, traditional Span-based...
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Article
Transverse momentum balance of dijets in Xe+Xe collisions at the LHC
We present a theoretical study of the medium modifications of the \(p_\textrm{T}\) p ...
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Article
Truncated loss-based Res2Net for non-Gaussian noise removal
Many current image denoising works focus on Gaussian noise removal. However, in many real-life applications, the noise in an image can follow non-Gaussian distributions, such as compressed speckle noise, salt-...
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Article
Open AccessExcessive accumulation of epicardial adipose tissue promotes microvascular obstruction formation after myocardial ischemia/reperfusion through modulating macrophages polarization
Owing to its unique location and multifaceted metabolic functions, epicardial adipose tissue (EAT) is gradually emerging as a new metabolic target for coronary artery disease risk stratification. Microvascular...
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Article
Exploring the immunological mechanism of Houttuynia cordata in the treatment of colorectal cancer through combined network pharmacology and experimental validation
To explore the potential mechanisms of Houttuynia cordata in the treatment of CRC using network pharmacology combined with experimental validation. The major active components of Houttuynia cordata were identifie...
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Article
Underlying Mechanism of Lysosomal Membrane Permeabilization in CNS Injury: A Literature Review
Lysosomes play a crucial role in various intracellular pathways as their final destination. Various stressors, whether mild or severe, can induce lysosomal membrane permeabilization (LMP), resulting in the rel...
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Article
Open AccessNirmatrelvir and ritonavir for inpatients with severe or critical COVID-19 beyond five days of symptom onset: a propensity score-matched, multicenter, retrospective cohort study
There is an urgent need for therapeutic strategies for inpatients with severe or critical COVID-19. The evaluation of the clinical benefits of nirmatrelvir and ritonavir (Nmr/r) for these patients beyond five ...
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Article
Open AccessJoint entity and relation extraction combined with multi-module feature information enhancement
The proposed method for joint entity and relation extraction integrates the tasks of entity extraction and relation classification by sharing the encoding layer. However, the method faces challenges due to inc...
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Article
A Diffusion Equation for Improving the Robustness of Deep Learning Speckle Removal Model
Speckle removal aims to smooth noise while preserving image boundaries and texture information. In recent years, speckle removal models based on deep learning methods have attracted a lot of attention. However...
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Article
Open AccessEffects of perineal massage at different stages on perineal and postpartum pelvic floor function in primiparous women: a systematic review and meta-analysis
Perineal massage, as a preventive intervention, has been shown to reduce the risk of perineal injuries and may have a positive impact on pelvic floor function in the early postpartum period. However, there is ...
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Article
Open AccessImpact of Immune Cells on Stroke Limited to Specific Subtypes: Evidence from Mendelian Randomization Study
Stroke is one of the common diseases that pose a severe threat to human health, with immune cells playing a crucial role in its onset and recovery. However, the specific mechanisms and causal relationships of ...
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Article
Optimization of silicone-modified acrylate nanoemulsion preparation process by response surface methodology
Nanoemulsions are colloidal dispersion systems that consist of oil, water, emulsifier, and co-emulsifier. They are isotropic and thermodynamically stable and possess either transparent or translucent propertie...
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Article
Open AccessCTSN: Predicting cloth deformation for skeleton-based characters with a two-stream skinning network
We present a novel learning method using a two-stream network to predict cloth deformation for skeleton-based characters. The characters processed in our approach are not limited to humans, and can be other ta...
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Article
Characteristics and Formation Mechanism of Oxide–Sulfide Complex Inclusions in High-Speed Railway Wheel Steel
The deleterious effects of brittle and rigid oxides on the quality of high-speed railway wheel steel can be mitigated by wrap** the oxides with sulfides. The investigation reveals the presence of three types...
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Article
Open AccessKey node identification for a network topology using hierarchical comprehensive importance coefficients
Key nodes are similar to important hubs in a network structure, which can directly determine the robustness and stability of the network. By effectively identifying and protecting these critical nodes, the rob...
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Article
Open AccessGene identification, expression analysis, and molecular docking of SAT and OASTL in the metabolic pathway of selenium in Cardamine hu**shanensis
Identification of selenium stress-responsive expression and molecular docking of serine acetyltransferase (SAT) and O-acetyl serine (thiol) lyase (OASTL) in Cardamine hu**shanensis.
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Article
On the Improved Conditions for Some Primal-Dual Algorithms
The convex problem of minimizing \(f({{\textbf {x}}})+g({{\textbf {x}}})+h({{\textbf {A}}}{{\textbf {x}}})\) ...
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Article
Organic ligand nanoarchitectonics for BiVO4 photoanodes surface passivation and cocatalyst grafting
Bismuth vanadate (BiVO4) is a promising photoanode material for efficient photoelectrochemical (PEC) water splitting, whereas its performance is inhibited by detrimental surface states. To solve the problem, here...
