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Article
A targetable HB-EGF–CITED4 axis controls oncogenesis in lung cancer
Aberrant epidermal growth factor (EGF) receptor (EGFR) signaling contributes to neoplastic initiation and progression in lung. Mutated EGFR has become as an important therapeutic target in lung cancer, whereas...
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Article
Protein tyrosine phosphatase PTPN3 inhibits lung cancer cell proliferation and migration by promoting EGFR endocytic degradation
Epidermal growth factor receptor (EGFR) regulates multiple signaling cascades essential for cell proliferation, growth and differentiation. Using a genetic approach, we found that Drosophila FERM and PDZ domain-c...
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Article
CITED2 functions as a molecular switch of cytokine-induced proliferation and quiescence
Transforming growth factor-α (TGF-α)-induced proliferation and transforming growth factor-β (TGF-β)-mediated quiescence are intricately balanced in normal lung-tissue homeostasis but are deregulated during neopla...
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Article
Surface Energy Anisotropy of Diffusion-Induced Ni3 A1 Crystals
Faceted crystals with well-defined {100}, {110}, and {1111 surfaces were observed in the interdiffusion zone during chemical interdiffusion of Ni/Ni 3 Al diffusion couple in the temperature range of 800°−1200°...
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Article
The Effect of Boron on Microhardness in Ni3 Al Polycrystals
In a recent MRS symposium, the effect of boron on grain boundary hardness (GBH) in Ni3Al was reported. Addition of 0.2 at.% of boron decreased the GBH in all three sets of alloys tested (24, 25, and 26 at.% Al). ...
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Article
Wet Oxidation in a Square Sandwich Composite of GaAs/AlAs/GaAs
Wet oxidation in a square sandwich composite, GaAs/AlAs/GaAs, with varying thickness of the AlAs layer was investigated in a temperature range of 400°C–480°C. At a given temperature and time, the oxidation dep...
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Article
Poster abstracts
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Article
Cited2 modulates TGF-β-mediated upregulation of MMP9
Cited (CBP/p300-interacting transactivators with glutamic acid (E)/aspartic acid (D)-rich C-terminal domain) 2, which is a CBP/p300-binding transcription co-activator without typical DNA-binding domains, has been...
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Article
Wet oxidation kinetics of AlAs at elevated temperatures
Wet oxidation in the AlAs layer sandwiched between two GaAs plates was investigated for the temperature range of 400 to 480 °C. The oxidation rate increased with increasing thickness of the AlAs layer. Theoret...
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Article
Decomposition and thermodynamic property of metastable Fe-Zn solid solutions produced by mechanical alloying
Thermal decomposition of supersaturated single-phase body-centered cubic (bcc) Fe100−xZnx (5≤ x ≤65 at.%) solid solutions, processed via mechanical alloying of high-purity metal powders, was investigated using x-...
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Article
Chemical stresses induced by grain-boundary diffusion in thin films
Chemical stresses induced by grain-boundary diffusion in thin films were analyzed. The stress distribution consisted of both tension and compression fields, and its characteristics were similar to those obtain...
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Article
Analytical study for hypersonic flow past an elliptic cone with longitudinal curvature
For hypersonic flow past an elliptic cone with longitudinal curvature, the outer-expansion analysis of shock layer and the inner-expansion analhsis of vortical layer are two major subjects in this research. Th...
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Article
Chemical stresses induced by grain-boundary diffusion
Based on Whipple-Suzuoka solutions, the chemical stresses induced by grain-boundary diffusion under constant- and instantaneous-source concentrations are investigated. For a finite boundary, the chemical stres...
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Article
Fractal characterization of the fracture surface of a high-strength low-alloy steel
The fractal dimension of fracture surfaces of a high-strength low-alloy steel (ASTM A710) has been measured using different ruler lengths. The fractal dimension increases with increasing impact toughness, E, a...
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Article
Nonlinear asymptotic theory of hypersonic flow past a circular cone
The hypersonic small-disturbance theory is reexamined in this study. A systematic and rigorous approach is proposed to obtain the nonlinear asymptotic equation from the Taylor-Maccoll equation for hypersonic f...
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Article
Thermal and mechanical properties of porous Y-PSZ/zircon composites
The thermal and mechanical properties of sintered porous composites of yttria-partially-stabilized-zirconia (Y-PSZ) and zircon (ZrSiO4) were investigated for a broad range of compositions. Fracture strengths of ...
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Article
An experimental study of the interaction of internal cracks in PMMA
Internal cracks in polymethyl methacrylate (PMMA) specimens were generated by pulsed laser light. The interactions of coplanar cracks, parallel cracks, and cracks in T and H configurations were investigated. T...
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Article
Analysis of mean square penetration depth in grain boundary diffusion
Exact and approximate expressions for mean square penetration depth (MSPD) in grain boundary diffusion are derived. The MSPDs in boundary diffusion are functionally different from those in lattice diffusion. T...
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Article
On the interaction of internal cracks in polymethyl methacrylate
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Article
Deformation mechanism map for creep in YBa2Cu3O7−x
A deformation mechanism map with grain size and stress as variables was constructed for creep in YBa2Cu3O7−xat 850 and 950 °C. Theoretical models of Nabarro-Herring, Coble, and power-law creep were used for the c...