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  1. No Access

    Article

    A targetable HB-EGF–CITED4 axis controls oncogenesis in lung cancer

    Aberrant epidermal growth factor (EGF) receptor (EGFR) signaling contributes to neoplastic initiation and progression in lung. Mutated EGFR has become as an important therapeutic target in lung cancer, whereas...

    C-H Hsieh, Y-T Chou, M-H Kuo, H-P Tsai, J-L Chang, C-W Wu in Oncogene (2017)

  2. No Access

    Article

    Protein tyrosine phosphatase PTPN3 inhibits lung cancer cell proliferation and migration by promoting EGFR endocytic degradation

    Epidermal growth factor receptor (EGFR) regulates multiple signaling cascades essential for cell proliferation, growth and differentiation. Using a genetic approach, we found that Drosophila FERM and PDZ domain-c...

    M-Y Li, P-L Lai, Y-T Chou, A-P Chi, Y-Z Mi, K-H Khoo, G-D Chang, C-W Wu in Oncogene (2015)

  3. Article

    CITED2 functions as a molecular switch of cytokine-induced proliferation and quiescence

    Transforming growth factor-α (TGF-α)-induced proliferation and transforming growth factor-β (TGF-β)-mediated quiescence are intricately balanced in normal lung-tissue homeostasis but are deregulated during neopla...

    Y-T Chou, C-H Hsieh, S-H Chiou, C-F Hsu, Y-R Kao, C-C Lee in Cell Death & Differentiation (2012)

  4. No Access

    Article

    Surface Energy Anisotropy of Diffusion-Induced Ni3 A1 Crystals

    Faceted crystals with well-defined {100}, {110}, and {1111 surfaces were observed in the interdiffusion zone during chemical interdiffusion of Ni/Ni 3 Al diffusion couple in the temperature range of 800°−1200°...

    T. C. Chou, Y. T. Chou in MRS Online Proceedings Library (2011)

  5. No Access

    Article

    The Effect of Boron on Microhardness in Ni3 Al Polycrystals

    In a recent MRS symposium, the effect of boron on grain boundary hardness (GBH) in Ni3Al was reported. Addition of 0.2 at.% of boron decreased the GBH in all three sets of alloys tested (24, 25, and 26 at.% Al). ...

    X. R. Qian, Y. T. Chou in MRS Online Proceedings Library (2011)

  6. No Access

    Article

    Wet Oxidation in a Square Sandwich Composite of GaAs/AlAs/GaAs

    Wet oxidation in a square sandwich composite, GaAs/AlAs/GaAs, with varying thickness of the AlAs layer was investigated in a temperature range of 400°C–480°C. At a given temperature and time, the oxidation dep...

    Sun-Chien Ko, Sanboh Lee, Y.T. Chou in Journal of Electronic Materials (2007)

  7. No Access

    Article

    Poster abstracts

    J. Ferrie, M. Shipley, F. Cappuccio, E. Brunner, M. Miller in Sleep and Biological Rhythms (2007)

  8. No Access

    Article

    Cited2 modulates TGF-β-mediated upregulation of MMP9

    Cited (CBP/p300-interacting transactivators with glutamic acid (E)/aspartic acid (D)-rich C-terminal domain) 2, which is a CBP/p300-binding transcription co-activator without typical DNA-binding domains, has been...

    Y-T Chou, H Wang, Y Chen, D Danielpour, Y-C Yang in Oncogene (2006)

  9. No Access

    Article

    Wet oxidation kinetics of AlAs at elevated temperatures

    Wet oxidation in the AlAs layer sandwiched between two GaAs plates was investigated for the temperature range of 400 to 480 °C. The oxidation rate increased with increasing thickness of the AlAs layer. Theoret...

    Sun-Chien Ko, Sanboh Lee, Hai-Lin Wang, Y. T. Chou in Journal of Materials Research (2003)

  10. No Access

    Article

    Decomposition and thermodynamic property of metastable Fe-Zn solid solutions produced by mechanical alloying

    Thermal decomposition of supersaturated single-phase body-centered cubic (bcc) Fe100−xZnx (5≤ x ≤65 at.%) solid solutions, processed via mechanical alloying of high-purity metal powders, was investigated using x-...

    F. Zhou, Y. T. Chou, E. J. Lavernia in Journal of Materials Research (2002)

  11. No Access

    Article

    Chemical stresses induced by grain-boundary diffusion in thin films

    Chemical stresses induced by grain-boundary diffusion in thin films were analyzed. The stress distribution consisted of both tension and compression fields, and its characteristics were similar to those obtain...

    W. L. Wang, Y. T. Chou, Sanboh Lee in Journal of Materials Research (2001)

  12. No Access

    Article

    Analytical study for hypersonic flow past an elliptic cone with longitudinal curvature

    For hypersonic flow past an elliptic cone with longitudinal curvature, the outer-expansion analysis of shock layer and the inner-expansion analhsis of vortical layer are two major subjects in this research. Th...

    Prof. S. -C. Lin, Y. -T. Chou in Acta Mechanica (1999)

  13. No Access

    Article

    Chemical stresses induced by grain-boundary diffusion

    Based on Whipple-Suzuoka solutions, the chemical stresses induced by grain-boundary diffusion under constant- and instantaneous-source concentrations are investigated. For a finite boundary, the chemical stres...

    W. L. Wang, Y. T. Chou, Sanboh Lee in Metallurgical and Materials Transactions A (1998)

  14. No Access

    Article

    Fractal characterization of the fracture surface of a high-strength low-alloy steel

    The fractal dimension of fracture surfaces of a high-strength low-alloy steel (ASTM A710) has been measured using different ruler lengths. The fractal dimension increases with increasing impact toughness, E, a...

    J. C Hsiung, Y. T Chou in Journal of Materials Science (1998)

  15. No Access

    Article

    Nonlinear asymptotic theory of hypersonic flow past a circular cone

    The hypersonic small-disturbance theory is reexamined in this study. A systematic and rigorous approach is proposed to obtain the nonlinear asymptotic equation from the Taylor-Maccoll equation for hypersonic f...

    Y. T. Chou, Prof. S. C. Lin, Prof. &Dean C. K. Feng in Acta Mechanica (1998)

  16. No Access

    Article

    Thermal and mechanical properties of porous Y-PSZ/zircon composites

     The thermal and mechanical properties of sintered porous composites of yttria-partially-stabilized-zirconia (Y-PSZ) and zircon (ZrSiO4) were investigated for a broad range of compositions. Fracture strengths of ...

    Y. P. **, Y. T. Chou in Material Research Innovations (1998)

  17. No Access

    Article

    An experimental study of the interaction of internal cracks in PMMA

    Internal cracks in polymethyl methacrylate (PMMA) specimens were generated by pulsed laser light. The interactions of coplanar cracks, parallel cracks, and cracks in T and H configurations were investigated. T...

    Y. Z LI, Y. T CHOU in Journal of Materials Science (1997)

  18. No Access

    Article

    Analysis of mean square penetration depth in grain boundary diffusion

    Exact and approximate expressions for mean square penetration depth (MSPD) in grain boundary diffusion are derived. The MSPDs in boundary diffusion are functionally different from those in lattice diffusion. T...

    Y. T. Chou, Y. Z. Li, C. T. Liu in Metallurgical and Materials Transactions A (1996)

  19. No Access

    Article

    On the interaction of internal cracks in polymethyl methacrylate

    Y. Z. Li, Y. T. Chou in Journal of Materials Science Letters (1996)

  20. No Access

    Article

    Deformation mechanism map for creep in YBa2Cu3O7−x

    A deformation mechanism map with grain size and stress as variables was constructed for creep in YBa2Cu3O7−xat 850 and 950 °C. Theoretical models of Nabarro-Herring, Coble, and power-law creep were used for the c...

    J. Yun, M. P. Harmer, Y. T. Chou in Journal of Materials Science (1995)

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