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  1. Article

    Correction to: Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55

    H. Wang, K. Song, T. L. Krebs, J. Yang, D. Danielpour in Oncogene (2022)

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    Article

    Hic-5 controls BMP4 responses in prostate cancer cells through interacting with Smads 1, 5 and 8

    Hydrogen peroxide-inducible clone-5 (Hic-5, or androgen receptor-associated protein 55) is a transforming growth factor-β-inducible LIM protein whose deregulation is implicated in the progression of prostate c...

    D T N Shola, H Wang, R Wahdan-Alaswad, D Danielpour in Oncogene (2012)

  3. Article

    Open Access

    The anti-apoptotic function of human αA-crystallin is directly related to its chaperone activity

    αA-crystallin is a molecular chaperone and an antiapoptotic protein. This study investigated the mechanism of inhibition of apoptosis by human αA-crystallin and determined if the chaperone activity of αA-crystall...

    N Pasupuleti, S Matsuyama, O Voss, A I Doseff, K Song, D Danielpour… in Cell Death & Disease (2010)

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  4. Article

    Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization

    Earlier, we have reported that 70 kDa subunit of Ku protein heterodimer (Ku70) binds and inhibits Bax activity in the cytosol and that ubiquitin (Ub)-dependent proteolysis of cytosolic Ku70 facilitates Bax-med...

    V Gama, J A Gomez, L D Mayo, M W Jackson, D Danielpour… in Cell Death & Differentiation (2009)

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    Article

    Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55

    We recently reported that hydrogen peroxide-inducible clone-5 (Hic-5, also named androgen receptor-associated protein 55) can bind to the transforming growth factor-β (TGF-β)-signaling regulator Smad3, thereby...

    H Wang, K Song, T L Krebs, J Yang, D Danielpour in Oncogene (2008)

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    Article

    Rb/E2F4 and Smad2/3 link survivin to TGF-β-induced apoptosis and tumor progression

    Survivin is a prosurvival protein overexpressed in many cancers through mechanisms that remain poorly explored, and is implicated in control of tumor progression and resistance to cancer chemotherapeutics. Her...

    J Yang, K Song, T L Krebs, M W Jackson, D Danielpour in Oncogene (2008)

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    Article

    ELAC2, a putative prostate cancer susceptibility gene product, potentiates TGF-β/Smad-induced growth arrest of prostate cells

    Transforming growth factor-β (TGF-β) elicits a potent growth inhibitory effect on many normal cells by binding to specific serine/threonine kinase receptors and activating specific Smad proteins, which regulate t...

    D Noda, S Itoh, Y Watanabe, M Inamitsu, S Dennler, F Itoh, S Koike… in Oncogene (2006)

  8. No Access

    Article

    Cited2 modulates TGF-β-mediated upregulation of MMP9

    Cited (CBP/p300-interacting transactivators with glutamic acid (E)/aspartic acid (D)-rich C-terminal domain) 2, which is a CBP/p300-binding transcription co-activator without typical DNA-binding domains, has been...

    Y-T Chou, H Wang, Y Chen, D Danielpour, Y-C Yang in Oncogene (2006)

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    Article

    Anti-oestrogens induce the secretion of active transforming growth factor beta from human fetal fibroblasts

    The clinical use of anti-oestrogens in breast cancer therapy has traditionally been restricted to tumours that contain measurable oestrogen receptor protein. However, it is now widely recognised that the clini...

    AA Colletta, LM Wakefield, FV Howell, KE van Roozendaal… in British Journal of Cancer (1990)