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Zinc ligand-disrupted recombinant human Endostatin: Potent inhibition of tumor growth, safety and pharmacokinetic profile

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  1. Article

    Open Access

    ENMD-1198, a novel tubulin-binding agent reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma(HCC) cells, and inhibits growth and vascularization in vivo

    Hepatocellular carcinoma (HCC) represents a highly vascularized tumor entity and the process of angiogenesis is essential for the growth of HCC. Importantly, the pro-angiogenic transcription factors HIF-1α and...

    Christian Moser, Sven A Lang, Akira Mori, Claus Hellerbrand, Hans J Schlitt… in BMC Cancer (2008)

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    Open Access

    Inhibition of E-Selectin (GMI-1271) or E-selectin together with CXCR4 (GMI-1359) re-sensitizes multiple myeloma to therapy

    Barbara Muz, Feda Azab, Mark Fiala, Justin King, Daniel Kohnen… in Blood Cancer Journal (2019)

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