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Article
Open AccessTherapy-induced senescent tumor cell-derived extracellular vesicles promote colorectal cancer progression through SERPINE1-mediated NF-κB p65 nuclear translocation
Cellular senescence frequently occurs during anti-cancer treatment, and persistent senescent tumor cells (STCs) unfavorably promote tumor progression through paracrine secretion of the senescence-associated se...
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Article
Visualization of ferromagnetic domains in vanadium-doped topological insulator thin films and heterostructures
Magnetically doped topological insulator (TI) thin films and related heterostructures have been extensively studied for years due to their exotic quantum transport properties and potential applications in low-...
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Article
Quercus dentata responds to Na2CO3 stress with salt crystal deposits: ultrastructure, and physiological–biochemical parameters of leaves
Our study elucidated that Q. dentata responds to Na2CO3 stress by excreting salt on the blade, accumulating osmotic protectants, and changing the cell ultrastructure and physiological-biochemical parameters of le...
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Article
Transcriptome analysis reveals the early resistance of zebrafish larvae to oxidative stress
Oxidative stress is one of most common environmental stresses encountered by fish, especially during their fragile larval stage. More and more studies are aimed at understanding the antioxidant defense mechani...
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Article
Open AccessLilac (Syringa oblata) genome provides insights into its evolution and molecular mechanism of petal color change
Color change during flower opening is common; however, little is understood on the biochemical and molecular basis related. Lilac (Syringa oblata), a well-known woody ornamental plant with obvious petal color cha...
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Article
Light-activated nitric-oxide overproduction theranostic nanoplatform based on long-circulating biomimetic nanoerythrocyte for enhanced cancer gas therapy
The limited intratumoral perfusion of nitric oxide (NO)-carrying nanoparticles into solid tumors caused by the inherent biological barriers in vivo greatly attenuates their generated efficacy. Herein, through ent...
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Article
Prediction model for mechanical properties of hot-rolled strips by deep learning
The prediction of the mechanical properties of hot-rolled strips is a very complex, highly dimensional and nonlinear problem, and the published models might lack reliability, practicability and generalization....
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Article
Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization
Keloid is a benign skin tumor characterized by its cell hyperproliferative activity, invasion into normal skin, uncontrolled growth, overproduction and deposition of extracellular matrices and high recurrence ...
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Article
An error prediction model of NC machining process considering multiple error sources
In flank milling process, machined surface is formed by the edge of the cutting tool while the position of tool is influenced by the movement of computer numerical control (CNC) machining axis and the status o...
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Article
Open AccessEfficacy and safety of tenofovir disoproxil fumarate in preventing vertical transmission of hepatitis B in pregnancies with high viral load
This study was a meta-analysis of the literature on the efficacy and safety of tenofovir disoproxil fumarate (TDF) in preventing vertical transmission of hepatitis B in pregnancies with high viral load. Four o...
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Chapter and Conference Paper
A Space Optimized Scatter Plot Matrix Visualization
This paper proposed a Space-Optimized Scatter Plot Matrix that used for the presentation of multi-dimensional dataset. This technique achieves the display space utilization in a 2D geometrical space. Our strat...
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Article
Open AccessThe catalytic role of the M2 metal ion in PP2Cα
PP2C family phosphatases (the type 2C family of protein phosphatases; or metal-dependent phosphatase, PPM) constitute an important class of signaling enzymes that regulate many fundamental life activities. All...
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Article
Effects of Zinc Transporter on Differentiation of Bone Marrow Mesenchymal Stem Cells to Osteoblasts
The differentiation of bone marrow mesenchymal stem cells (MSCs) into osteoblasts is a crucial step during bone formation. However, the exact mechanisms regulating the early stages of osteogenic differentiatio...
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Chapter and Conference Paper
Education Image Retrieval Method Using Moment Invariants
Shape-based image retrieval is an important part of image retrieval. According to the shape of moment invariant features of image, a new method for shape based image retrieval is presented. Firstly the edges i...
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Article
The Determination of PCBs in Meat and Sea Food by GC-QqQ-MS/MS
A new method was developed for the determination of 12 polychlorinated biphenyls (PCBs) in meat and sea food by gas chromatography coupled to triple quadrupole mass spectrometry using selected reaction monitor...
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Article
Gluococorticoid could influence extracellular matrix synthesis through Sox9 via p38 MAPK pathway
Here, we used glucocorticoid as an apoptosis inducer to study how glucocorticoid could accelerate cartilage degeneration and the responsible signal pathway. Human chondrocytes were isolated from knee joints ga...
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Chapter and Conference Paper
Computer-Mediated Communication in Education
Synchronous communication techniques allow participants to contribute from locations at the same time. The tools available include chat, desktop videoconferencing and GroupWare. Although these online technique...
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Article
Analysis of time-course gene expression profiles of sinusoidal endothelial cells during liver regeneration in rats
Liver regeneration (LR) after partial hepatectomy (PH) requires the coordinate contribution of different cell types. Liver sinusoidal endothelial cells (LSECs), representing the largest population of nonparenc...
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Article
Preparation, characterization, in vivo and in vitro studies of arsenic trioxide Mg-Fe ferrite magnetic nanoparticles
MgFe2O4 magnetic nanoparticle composed of As2O3 (As2O3-MNPs) were prepared and their in vitro and in vivo characteristics were studied.
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Article
Serial Expression Analysis of Liver Regeneration-Related Genes in Rat Regenerating Liver
We investigated the gene expression changes in rat hepatic restoration with Rat Genome 230 2.0 chip containing 11,789 known genes and 13,231 unknown genes (taking up 90 percent of rat whole genome) following a...