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Chapter and Conference Paper
Detection of Secondary Insults by Brain Tissue pO2 and Bedside Microdialysis in Severe Head Injury
We evaluated bedside cerebral on-line microdialysis for early detection of cerebral hypoxia in patients with traumatic brain injury. 24 severely head injured patients (Glasgow Coma Score ≤ 8) were studied. Pat...
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Chapter and Conference Paper
Intracranial Compliance as a Bed-Side Monitoring Technique in Severely Head-Injured Patients
A recently developed monitoring technology makes an on-line assessment of intracranial compliance (ICC) possible. Aims of our research: 1. Course and values of ICC (critical threshold: <0.5 ml/ mmHg) in episod...
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Chapter and Conference Paper
Temporal Profiles of Extracellular Nitric Oxide Metabolites Following Aneurysmal Subarachnoid Hemorrhage
The temporal profile of nitric oxide metabolite concentrations i.e. nitrite and nitrate (NO x ) was investigated in brain parenchyma of patients following aneurysmal subarachnoid...
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Chapter and Conference Paper
Decompressive Craniectomy Following Traumatic Brain Injury: ICP, CPP and Neurological Outcome
Decompressive craniectomy is often the final option in the management of posttraumatic intracranial hypertension. Aim of this study was to investigate the effect of secondary decompression on intracranial pres...
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Article
Treatment of a cavernous sinus dural arteriovenous fistula by deep orbital puncture of the superior ophthalmic vein
In a patient with progressive ophthalmological problems, including uncontrolled intraocular pressure related to a cavernous sinus dural arteriovenous fistula, urgent intervention may be necessary to prevent p...
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Chapter and Conference Paper
On-line Microdialysis Following Aneurysmal Subarachnoid Hemorrhage
Cerebral vasospasm (VSP) is one of the feared sequelae of subarachnoid hemorrhage (SAH). Symp- tomatic VSP, i.e. VSP leading to delayed ischemic neurological deficits (DIND), is still observed in approximately...
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Chapter and Conference Paper
Time Course of Various Interstitial Metabolites Following Subarachnoid Hemorrhage Studied by on-Line Microdialysis
Subarachnoid hemorrhage (SAH) is one of the most devastating of all cerebrovascular disorders [10]. One of the most serious complications of SAH remains vasospasm [3, 9]. Bedside cerebral microdialysis is a recen...
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Article
Lipomatous secretory meningioma: case report and review of the literature
Secretory meningioma is a rare entity which may be characterised by imaging features unusual for other subtypes of meningoma, such as low attenuation on CT, high (fat-tissue equivalent) signal intensity on T1...
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Article
Oxymetrie im Bulbus jugularis bei komatösen Patienten
Das Monitoring der Sauerstoffsättigung im Bulbus venae jugularis (auch Bulbusoxymetrie genannt) ist eine Methode zur kontinuierlichen Erfassung der globalen zerebrovenösen Sauerstoffsättigung (SjvO2). Diese kan...
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Article
Multimodal Cerebral Monitoring in Comatose Head-Injured Patients
Monitoring of comatose patients in the neurosurgical intensive care unit (NICU) is constantly extended by the development of new methods for monitoring of cerebral function, metabolism and oxygenation. To sim...
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Article
Long term follow up in lumbar spinal stenosis
In a retrospective study the charts of 72 patients who had decompressive surgery for lumbar stenosis between 1987 and 1990 were evaluated. Mean first follow up was 2.5 years (range 1.5 years to 3.5 years). A s...
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Chapter and Conference Paper
Bifrontal Measurements of Brain Tissue-PO2 in Comatose Patients
The purpose of this study was to compare brain tissue-PO2 (PtiO2) in lesioned vs. non-lesioned brain tissue.
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Chapter and Conference Paper
Cerebral Oxygenation in Contusioned vs. Nonlesioned Brain Tissue: Moniting of PtiO2 with Licox and Paratrend
Brain tissue PO2 in severely head injured patients was monitored in parallel with two different PO2-microsensors (Licox and Paratrend). Three different locations of sensor placement were chosen: (1) both catheter...
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Chapter and Conference Paper
Monitoring of Brain Tissue PO2 in Traumatic Brain Injury: Effect of Cerebral Hypoxia on Outcome
This study investigates the effect of hypoxic brain tissue PO2 on outcome, and examines the incidence of possible causes for cerebral hypoxia.
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Chapter and Conference Paper
Magnetic Resonance Imaging Studies with Cluster Algorithm for Characterization of Brain Edema after Controlled Cortical Impact Injury (CCII)
Objective of this study was the characterization of traumatic brain injury induced by a “Controlled Cortical Impact” with magnetic resonance imaging techniques. The impact was applied to the intact dura of the...
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Chapter and Conference Paper
Influence of Hyperventilation on Brain Tissue-PO2, PCO2, and pH in Patients with Intracranial Hypertension
A harmful effect of prolonged hyperventilation on outcome has been shown in comatose patients after severe head injury. The purpose of this study was to assess the acute effect of moderate hyperventilation for...
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Article
Different release of cytokines into the cerebrospinal fluid following surgery for intra- and extra-axial brain tumours
To elucidate the role of cytokines in brain repair processes and in local inflammation after neurosurgical procedures, cerebrospinal fluid (CSF) samples from 8 patients with intra-axial tumours and 8 patients ...
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Chapter and Conference Paper
Effect of Tromethamine (THAM) on Infarct Volume Following Permanent Middle Cerebral Artery Occlusion in Rats
This study investigates the influence on tromethamine (THAM) on ischemic volume induced by permanent middle cerebral artery occlusion (MCAO) in rats.
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Chapter
Monitoring of Cerebral Oxygenation in Traumatic Brain Injured Patients
For many years, the sequel of traumatic brain injury distinguished between primary and secondary damage. Primary damage, caused by the physical forces associated with the trauma, occurs more or less instantly ...
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Article
Initial clinical experience with spiral CT and 3D arterial reconstruction in intracranial aneurysms and arteriovenous malformations
We studied 32 consecutive patients with known or suspected cerebrovascular abnormalities studied with spiral CT following a intravenous bolus injection of iodinated contrast medium with a power injector. Flow ...