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Chapter and Conference Paper
Einfluß von Spender/Empfänger HLA-B Übereinstimmungen auf das Transplantatüberleben bei lebertransplantierten Patienten mit HBV- Zirrhose
Der Verlauf von Patienten, die wegen terminaler Leberzirrhose auf dem Boden von Viruserkrankungen orthotop lebertransplantiert worden sind, wird oft durch Reinfektionen des Transplantates mit dem Virus kompliz...
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Article
Effective therapy for hepatic M. Osler with systemic hypercirculation by ligation of the hepatic artery and subsequent liver transplantation
Hereditary hemorrhagic teleangiectasia, or M. Osler (Osler-Weber-Rendu disease), is an autosomal dominant, systemic fibrovascular dysplasia. This may lead to increased liver blood flow from arteriovenous fist...
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Chapter and Conference Paper
Ergebnisse nach Lebertransplantation bei Patienten mit Hämochromatose
Recent reports suggest a poor outcome of orthotopic liver transplantation for patients with hemochromatosis. Nine of the 1016 patients (0.9%) underwent transplantation because of hemochromatosis. Four of nine ...
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Chapter and Conference Paper
Verbesserung der virologischen Ansprechrate durch Therapie mit pegyliertem Interferon alpha-2-b plus Ribavirin nach Lebertransplantation bei Hepatitis-C-Zirrhose
Recurrence of hepatitis C (HCV) infection after OLT for HCV cirrhosis is almost universal and approximately 10% of patients develop cirrhosis after OLT for HCV. Common treatments with ribavirin and interferon ...
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Article
Adult living donor liver transplantation: living donation of the right liver lobe
Adult living donor liver transplantation (LDLT) has become a routine treatment option for patients waiting for liver transplantation. In European and North American countries, LDLT for adult recipients is main...
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Chapter and Conference Paper
Synergistischer Effekt von Erythropoietin und Curcumin auf Regenerationsstörungen der Leber
Serious postoperative infections can inhibit regeneration after liver resection. It has been shown, that hematopoietic growth factors like GCSF (granulocyte colony stimulating factor) or erythropoietin (EPO) c...
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Chapter and Conference Paper
Inhibition of Sonic Hedgehog signaling reduces tumor growth in pancreatic cancer in vitro and in vivo
Introduction: Activation of the hedgehog signal transduction pathway, triggered by hedgehog binding to the transmembrane receptor PTCH or by mutations in the PTCH gene, plays an important role in...
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Article
Lebertransplantation bei primär sklerosierender Cholangitis und Colitis ulcerosa
Das langfristige Überleben ist sowohl bei asymptomatischen wie auch bei symptomatischen Patienten mit primär sklerosierender Cholangitis (PSC) beeinträchtigt. Dies resultiert unter anderem aus der erhöhten Inz...
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Article
Hepatitis-B- und -C-Reinfektion: Prophylaxe und Therapie
Die orthotope Lebertransplantation (OLT) hat die Behandlung der terminalen Leberinsuffizienz fundamental verändert, Zehnjahreslangzeitüberlebensraten liegen inzwischen bei etwa 70%. Die Langzeitergebnisse für ...
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Article
Recurrent intrahepatic cholangiocarcinoma: single-center experience using repeated hepatectomy and radiofrequency ablation
Intrahepatic cholangiocarcinoma (IHC) is a rare liver malignancy with a rising incidence worldwide. Since no standard treatment has been established so far, the aim of this study was to assess the safety and e...
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Article
Protektives Ileostoma vs. protektives Transversostoma
Im Rahmen der kolorektalen Notfallchirurgie und der Chirurgie des tiefen Rektumkarzinoms ist die Anlage eines protektiven temporären Stomas nach wie vor unverzichtbar. Die Lokalisation des Stomas wird jedoch w...
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Article
Liver Transplantation for Alcohol-Related Cirrhosis: A Single Centre Long-Term Clinical and Histological Follow-Up
Alcohol-induced liver cirrhosis is one of the leading indications for liver transplantation today. Due to the general organ shortage and continuous deaths on the waiting list there has been some debate on the ...
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Article
Impact of pressure and gas type on adhesion formation and biomaterial integration in laparoscopy
Laparoscopic mesh repair of inguinal and incisional hernias has been widely adopted. Nevertheless, knowledge about the impact of pneumoperitoneum on mesh integration is rare. The present study investigates pre...
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Article
Primary anastomosis with a defunctioning stoma versus Hartmann's procedure for perforated diverticulitis—a comparison of stoma reversal rates
The ideal treatment of patients with perforated diverticulitis is still controversial. Hartmann's procedure has been the treatment of choice for decades, but primary anastomosis with a defunctioning stoma has ...
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Article
Influence of Intraoperative Radiotherapy (IORT) on Perioperative Outcome after Surgical Resection of Rectal Cancer
Intraoperative radiotherapy (IORT) for locally advanced or recurrent rectal cancer as an integral part of multimodal treatment might be an option to reduce local cancer recurrence. The aim of the present study...
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Article
Is Current Perioperative Practice in Hepatic Surgery Based on Enhanced Recovery After Surgery (ERAS) Principles?
The worldwide introduction of multimodal enhanced recovery programs has also changed perioperative care in patients who undergo liver resection. This study was performed to assess current perioperative practic...
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Article
In vivo characterisation of the inflammatory reaction following mesh implantation in transgenic mice models
Hernia repair with prosthetic meshes represents one of the most common surgical procedures in the field of surgery. This intervention is always associated with an ensuing inflammatory response, angiogenesis an...
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Article
Postoperative outcome in premature infants with open abdomen
Premature infants treated with laparostomy in the first days of their life represent a group of complex patients with high morbidity and mortality rates. Laparostomy is a surgical treatment method in which the...
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Article
Spinal anesthesia for inguinal hernia repair in infants: a feasible and safe method even in emergency cases
Inguinal hernia repair is the most frequently performed surgical procedure in infants and children. Especially in premature infants, prevalence reaches up to 30 % in coincidence with high rates of incarceratio...
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Article
In vivo MRI visualization of parastomal mesh in a porcine model
After two-dimensional plane MRI-visible mesh implants could be successfully visualized in phantom and small animal model, the aim of the underlying study was to explore the feasibility of an MRI visualization ...