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  1. Article

    Open Access

    The microstructure in the placenta is influenced by the functional diversity of HLA-G allelic variants

    The main expression sites of HLA-G are human extravillous trophoblast cells. The interaction of HLA-G with uterine NK cells promotes their maturation and differentiation into decidual NK (dNK) cells. dNK cells...

    F. Stieglitz, A. A. Celik, C. von Kaisenberg, M. A. Camps, R. Blasczyk in Immunogenetics (2019)

  2. Article

    Open Access

    Lentivirus-induced ‘Smart’ dendritic cells: Pharmacodynamics and GMP-compliant production for immunotherapy against TRP2-positive melanoma

    Monocyte-derived conventional dendritic cells (ConvDCs) loaded with melanoma antigens showed modest responses in clinical trials. Efficacy studies were hampered by difficulties in ConvDC manufacturing and low ...

    B S Sundarasetty, L Chan, D Darling, G Giunti, F Farzaneh, F Schenck in Gene Therapy (2015)

  3. No Access

    Chapter

    Antigen-Antikörper-Reaktion: Grundlagen serologischer Methoden

    Der Nachweis von Antigenen oder Serumantikörpern spielt in der medizinischen Diagnostik eine bedeutende Rolle.

    Prof. Dr. S. H. E. Kaufmann, R. Blasczyk in Basiswissen Immunologie (2014)

  4. Article

    Open Access

    Heat Shock Protein 70 (HSP70) induces cytotoxicity of T-helper cells

    C Figueiredo, M Wittmann, D Wang, R Dressel, R Blasczyk in Cell Communication and Signaling (2009)

  5. Article

    Open Access

    Human calreticulin can act as adjuvant in the maturation of antigen presenting cells

    A Bajor, J Hinrichs, C Figueiredo, M Wittmann in Cell Communication and Signaling (2009)

  6. Article

    Open Access

    NKG2A silencing in effector cells to improve effectivity of cell based therapeutics

    C Figueiredo, J Zenk, B Eiz-Vesper, R Blasczyk in Cell Communication and Signaling (2009)

  7. No Access

    Article

    Allogeneic stem cell transplantation from related and unrelated donors for aplastic anaemia in adults—a single-centre experience

    Aplastic anaemia (AA) is a rare bone marrow failure syndrome treated either by immunosuppressive therapy or allogeneic stem cell transplantation (SCT). At present, no randomised clinical trials evaluating both...

    S. Buchholz, E. Dammann, Ch. Koenecke, M. Stadler, A. Franzke in Annals of Hematology (2008)

  8. No Access

    Article

    Reply to the letter by Shaw et al

    H A Elsner, R Blasczyk in Bone Marrow Transplantation (2004)

  9. No Access

    Article

    A comparative study of adverse reactions occurring after administration of glycosylated granulocyte colony stimulating factor and/or dexamethasone for mobilization of neutrophils in healthy donors

    Both granulocyte colony-stimulating factor (G-CSF) and dexamethasone (DXM) are used for neutrophil (PMN) mobilization and collection. This prospective study was aimed to evaluate and compare the rate, severity...

    H. G. Heuft, L. Goudeva, R. Blasczyk in Annals of Hematology (2004)

  10. No Access

    Article

    Presentation assessment of minor histocompatibility antigens by predictive proteasomal cleavage analysis

    Minor histocompatibility peptides (mHps) derived from polymorphic segments of endogenous proteins are thought to be targets for graft-versus-host and graft-versus-leukemia reactions after HLA-identical stem ce...

    B. Khattab, B. Eiz-Vesper, A. Ganser, B. Hertenstein, R. Blasczyk in Annals of Hematology (2004)

  11. No Access

    Article

    HistoCheck: rating of HLA class I and II mismatches by an internet-based software tool

    HLA polymorphism is a major barrier for hematopoietic stem cell and solid organ transplantation. To estimate the allogeneic potential between HLA-mismatched stem cell donor/recipient pairs, we recently propose...

    H-A Elsner, D DeLuca, J Strub, R Blasczyk in Bone Marrow Transplantation (2004)

  12. No Access

    Article

    The nature of introns 4–6 suggests reduced lineage specificity in HLA-B alleles

    For most HLA-B alleles, coding sequences of the 3′ part of the genes still need to be determined, and sequences of the 3′ noncoding regions have yet to be studied systematically. In this study, we have determi...

    H-A Elsner, K Baengeroth, R Blasczyk in Genes & Immunity (2003)

  13. No Access

    Article

    Second German consensus on immunogenetic donor search for allotransplantation of hematopoietic stem cells

    The present paper summarizes the results of the second German consensus meeting on immunogenetic donor search for allotransplantation of hematopoietic stem cells held in Essen in November 1999 under the auspi...

    H. Ottinger, C. Müller, S. Goldmann, E. Albert, R. Arnold in Annals of Hematology (2001)

  14. No Access

    Article

    Treatment of relapse after allogeneic bone marrow transplantation with unmanipulated G-CSF-mobilized peripheral blood stem cell preparation

    Donor lymphocyte infusions (DLI) are an effective treatment of leukemia relapse after allogeneic bone marrow transplantation. Undesired side-effects are the development of graft-versus-host disease (GVHD) and ...

    W Siegert, J Beyer, D Kingreen, R Blasczyk, H Baurmann in Bone Marrow Transplantation (1998)

  15. No Access

    Chapter and Conference Paper

    Einfluß von Spender/Empfänger HLA-B Übereinstimmungen auf das Transplantatüberleben bei lebertransplantierten Patienten mit HBV- Zirrhose

    Der Verlauf von Patienten, die wegen terminaler Leberzirrhose auf dem Boden von Viruserkrankungen orthotop lebertransplantiert worden sind, wird oft durch Reinfektionen des Transplantates mit dem Virus kompliz...

    U. P. Neumann, J. M. Langrehr, R. Blasczyk, M. Lang in Chirurgisches Forum ’98 (1998)

  16. No Access

    Chapter

    New HLA Ty** Methods

    The human major histocompatibility complex (MHC) was discovered during studies initiated by J. Dausset, R. Payne and J. J. van Rood describing a genetically inherited system of alloantigens [1–3]. Initially hi...

    R. Blasczyk in New Diagnostic Methods in Oncology and Hematology (1998)

  17. No Access

    Article

    German consensus on immunogenetic donor search for transplantation of allogeneic bone marrow and peripheral blood stem cells

    In Germany allotransplantation of bone marrow or peripheral blood stem cells is presently performed by 34 different teams operating more or less independently. Thus, strategies of immunogenetic donor search, u...

    HD Ottinger, E Albert, R Arnold, DW Beelen, R Blasczyk in Bone Marrow Transplantation (1997)