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  1. Article

    Open Access

    Evaluation of oral care using MA-T gel for high-risk patients: a pilot study

    Oral care with gel is a common method for preventing aspiration in high-risk patients. An oral care gel is used to clean and moisturize the oral cavity. However, the effects of gel care on the oral bacteria re...

    Hitomi Ono-Minagi, Nao Gojo, Tsutomu Nohno, Tsuyoshi Inoue in BMC Oral Health (2023)

  2. Article

    Open Access

    Erratum to: miR-487b, miR-3963 and miR-6412 delay myogenic differentiation in mouse myoblast-derived C2C12 cells

    Naoki Katase, Kumiko Terada, Takahiro Suzuki, Shin-ichiro Nishimatsu in BMC Cell Biology (2016)

  3. Article

    Open Access

    miR-487b, miR-3963 and miR-6412 delay myogenic differentiation in mouse myoblast-derived C2C12 cells

    Skeletal muscle differentiation is a multistep, complex pathway in which several important signaling molecules are involved. Recently, microRNAs (miRNAs), endogenous non-coding small RNAs that regulate mRNAs, ...

    Naoki Katase, Kumiko Terada, Takahiro Suzuki, Shin-ichiro Nishimatsu in BMC Cell Biology (2015)

  4. Article

    Open Access

    Canonical Wnt signaling is involved in switching from cell proliferation to myogenic differentiation of mouse myoblast cells

    Wnt/β-catenin signaling is involved in various aspects of skeletal muscle development and regeneration. In addition, Wnt3a and β-catenin are required for muscle-specific gene transcription in embryonic carcino...

    Shingo Tanaka, Kumiko Terada, Tsutomu Nohno in Journal of Molecular Signaling (2011)

  5. No Access

    Article

    Ribosomal ITS Sequences Allow Resolution of Freshwater Sponge Phylogeny with Alignments Guided by Secondary Structure Prediction

    Freshwater sponges include six extant families which belong to the suborder Spongillina (Porifera). The taxonomy of freshwater sponges is problematic and their phylogeny and evolution are not well understood. ...

    Valeria Itskovich, Andrey Gontcharov, Yoshiki Masuda in Journal of Molecular Evolution (2008)

  6. Article

    Open Access

    Nuclear localization of beta-catenin involved in precancerous change in oral leukoplakia

    Oral leukoplakia is a precancerous change developed in the oral mucosa, and the mechanism that oral leukoplakia becomes malignant through atypical epithelium is not known. Here we compared the β-catenin expres...

    Kosei Ishida, Satoshi Ito, Naoyuki Wada, Hiroyo Deguchi, Tsuyoshi Hata in Molecular Cancer (2007)

  7. No Access

    Article

    Immunosuppressant FK506 Induces Neurite Outgrowth in PC12 Mutant Cells with Impaired NGF-Promoted Neuritogenesis via a Novel MAP Kinase Signaling Pathway

    We obtained a drug-hypersensitive PC12 mutant cell (PC12m3), in which neurite outgrowth was strongly stimulated by various drugs such as FK506, calcimycin and cAMP, under the condition of NGF treatment. The fr...

    Yoshio Kano, Tsutomu Nohno, Toru Hasegawa, Rei Takahashi in Neurochemical Research (2002)

  8. No Access

    Article

    Paraquat-induced gene expression in rat lung tissues using a differential display reverse transcription-polymerase chain reaction

    Increased formation of reactive oxygen species is a cause of paraquat (PQ)-induced injury and also provides a link between the signaling pathways and transcriptional events that regulate the expression of a l...

    Masafumi Tomita, Tsutomu Nohno, Toshiko Okuyama in Archives of Toxicology (2002)

  9. No Access

    Article

    Expression of the fibroblast growth factor receptor 1–4 genes in glomeruli in anti-Thy1.1 mesangial proliferative glomerulonephritis

    Basic fibroblast growth factor (FGF2) is generally known to induce proliferation of cultured mesangial cells and is expressed in proliferative mesangial cells in anti-Thy1.1 mesangial proliferative glomerulone...

    Y. Jyo-Oshiro, Tamaki Sasaki, Yasuhiko Kawakami, Tsutomu Nohno in Virchows Archiv (1999)

  10. No Access

    Article

    Retinoic acid induces polarizing activity but is unlikely to be a morphogen in the chick limb bud

    RETINOIC acid is a putative morphogen in limb formation in the chick and other vertebrates1-5. In chick limb formation, it is thought that retinoic acid is released from the zone of polarizing activity (ZPA) and ...

    Sumihare Noji, Tsutomu Nohno, Eiki Koyama, Kohki Muto, Kazuhiko Ohyama in Nature (1991)

  11. No Access

    Article

    Cloning and complete nucleotide sequence of the Escherichia coli glutamine permease operon (glnHPQ)

    The glutamine permease operon encoding the high-affinity transport system of glutamine in Escherichia coli could be cloned in one of the mini F plasmids, but not in pBR322 or pACYC184, by selection for restoratio...

    Tsutomu Nohno, Taiichi Saito, Jen-shiang Hong in Molecular and General Genetics MGG (1986)