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Article
Open AccessAnti-nucleocapsid antibodies enhance the production of IL-6 induced by SARS-CoV-2 N protein
A cytokine storm induces acute respiratory distress syndrome, the main cause of death in coronavirus disease 2019 (COVID-19) patients. However, the detailed mechanisms of cytokine induction due to severe acute...
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Article
Xanthogranulomatous cholecystitis: a review of 31 patients
Xanthogranulomatous cholecystitis (XGC) is a rare inflammatory gallbladder disease which is difficult to diagnose and treat; XGC may be confused with gallbladder cancer. The present study aimed to evaluate the...
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Article
A case of bilateral methotrexate-associated diffuse large B-cell lymphomas of the breasts with unique clinical presentation and outcome
A 54-year-old woman on methotrexate (MTX) treatment developed reddish skin change in her right breast. Mammography and ultrasound showed no masses in the breasts but bilateral mammary glands presented diffuse ...
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Article
Open AccessDetermining the difference in the efficacy and safety of self-expandable metallic stents as a bridge to surgery for obstructive colon cancer among patients in the CROSS 0 group and those in the CROSS 1 or 2 group: a pooled analysis of data from two Japanese prospective multicenter trials
This study compared the feasibility and safety of endoscopic placement of self-expandable metallic stents (SEMSs) as a bridge to surgery (BTS) between patients with obstructive colorectal cancer (CRC) classifi...
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Article
Open AccessA clinical comparison of laparoscopic versus open appendectomy for the treatment of complicated appendicitis: historical cohort study
Appendectomy is one of the most common operations. Laparoscopic appendectomy (LA) is considered first-line treatment, but the use of LA for treatment of complicated appendicitis remains controversial. Here, we...
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Article
Open AccessCalcification and abscess formation around the catheter tip of a central venous access port: a case report
Thrombosis of the internal jugular vein occasionally occurs in association with long-term placement of a central venous catheter; however, such complications rarely involve calcification within the blood vesse...
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Article
Additional surgery after endoscopic submucosal dissection for colorectal cancer: a review of 53 cases
Endoscopic submucosal dissection (ESD) allows the en bloc resection of tumors and is particularly indicated for T1 colorectal cancer. The number of patients undergoing additional surgery after colorectal ESD i...
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Article
Open AccessSelf-expandable metallic stenting as a bridge to surgery for malignant colorectal obstruction: pooled analysis of 426 patients from two prospective multicenter series
Self-expandable metallic stenting (SEMS) for malignant colorectal obstruction (MCO) as a bridge to elective surgery (BTS) is a widely used procedure. The aim of this study was to assess short-term outcomes of ...
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Article
A prospective multicenter study on self-expandable metallic stents as a bridge to surgery for malignant colorectal obstruction in Japan: efficacy and safety in 312 patients
Endoscopic stenting with a self-expandable metallic stent (SEMS) is a widely accepted procedure for malignant colonic obstruction. The Colonic Stent Safe Procedure Research Group conducted the present prospect...
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Article
Paraquat-induced gene expression in rat kidney
Paraquat, one of the most widely used herbicides, is highly toxic to humans and animals. There is much information regarding its toxic effects on the lungs, but less is known about its toxicity in other organs...
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Article
Involvement of IL-10 and Bcl-2 in resistance against an asbestos-induced apoptosis of T cells
To analyze the possibility that immunological alteration in asbestos-related diseases (ARDs) such as asbestosis (ASB) and malignant mesothelioma (MM) may affect the progression of cancers, a human adult T cell...
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Article
Consecutive administration of paraquat to rats induces enhanced cholesterol peroxidation and lung injury
It is our hypothesis that as a consequence of increased oxidative stress, rats develop lung injury with increased cholesterol-derived hydroperoxides and oxysterols in lung after consecutive exposure of the rat...
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Article
Paraquat-induced gene expression in rat lung tissues using a differential display reverse transcription-polymerase chain reaction
Increased formation of reactive oxygen species is a cause of paraquat (PQ)-induced injury and also provides a link between the signaling pathways and transcriptional events that regulate the expression of a l...
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Article
Quantitation of the hydroxyl radical adducts of salicylic acid by micellar electrokinetic capillary chromatography: oxidizing species formed by a Fenton reaction
There has been controversy concerning the products formed by a Fenton reaction. We determined the hydroxyl radical (•OH) generated in a Fenton reaction system with no iron chelator using micellar electrokinetic c...
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Article
Effect of paraquat on the malondialdehyde level in rat liver microsomes (in vitro)
Toxicosis due to paraquat, a redox cycling xenobiotic, is still a subject of much debate. In the present study on lipid peroxidation, paraquat had a biphasic effect on the malondialdehyde (MDA) level in rat li...
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Article
High-Performance Liquid Chromatographic Determination of Urinary Malondialdehyde as p-Nitrophenylhydrazine Derivative
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Article
Free malondialdehyde levels in the urine of rats intoxicated with paraquat
We examined the excretion of free malondialdehyde (MDA) in the urine of rats to which a herbicide, Gramoxone, had been orally administered. The herbicide was administered for 2 days at a dose of 60 mg paraquat...
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Article
Urinary excretion of p-hydroxylated methamphetamine metabolites in man
p-Hydroxymethamphetamine and p-hydroxyamphetamine in urine samples from methamphetamine addicts were analyzed by high-performance liquid chromatography-electrochemistry (HPLC-EC). The urine samples were hydrolyz...
