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  1. Article

    Open Access

    Swallowing-related muscle inflammation and fibrosis induced by a single dose of radiation exposure in mice

    Although radiotherapy is commonly used to treat head and neck cancer, it may lead to radiation-associated dysphagia (RAD). There are various causes of RAD, however, the mechanism has not yet been fully identif...

    Shuntaro Soejima, Chia-Hsien Wu, Haruna Matsuse in Laboratory Animal Research (2024)

  2. No Access

    Article

    Investigation of Transition Phenomenon from Rotating Cavitation to Attached Asymmetric Cavitation by Coupled Analysis of One-Dimensional Flow Path Model of 3-Blade Inducer and Shaft Vibration System

    During the development process of the turbopump for a rocket engine, various problems of shaft vibration have been reported. Among them, vibration problems caused by dynamic fluid flow phenomena in the inducer...

    Tsuyoshi Inoue, Hirohisa Ohama, Yuki Imaeda in Journal of Vibration Engineering & Technol… (2024)

  3. No Access

    Chapter and Conference Paper

    Influence of Slight Gravitational Effect on the Characteristics of Onset Speeds of Instability and Stability in the Vertical Rotating Shaft Supported by Journal Bearing

    In rotating machinery such as vertical pumps supported vertically by sliding bearings, it is difficult to predict the dynamic characteristics because of the strong influence of the nonlinearity of the sliding ...

    Li Fan, Tsuyoshi Inoue, Akira Heya in Proceedings of the 11th IFToMM Internation… (2024)

  4. No Access

    Chapter and Conference Paper

    Modeling of the Divergently Worn Annular Seal for the Two-Way Coupled Fluid–Structure Interaction Analysis of Shaft Vibration and Clearance Flow

    One of the causes of shaft vibration in turbomachinery is the rotordynamic (RD) fluid force. RD fluid force has a significant impact on the stability of the system, so it is necessary to carry out shaft vibrat...

    Shogo Kimura, Tsuyoshi Inoue, Hiroo Taura in Proceedings of the 11th IFToMM Internation… (2024)

  5. Article

    Open Access

    Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody

    FtsZ polymerizes into protofilaments to form the Z-ring that acts as a scaffold for accessory proteins during cell division. Structures of FtsZ have been previously solved, but detailed mechanistic insights ar...

    Junso Fujita, Hiroshi Amesaka, Takuya Yoshizawa, Kota Hibino in Nature Communications (2023)

  6. Article

    Open Access

    Alpha 7 nicotinic acetylcholine receptors signaling boosts cell-cell interactions in macrophages effecting anti-inflammatory and organ protection

    Activation of the cholinergic anti-inflammatory pathway (CAP) via vagus nerve stimulation has been shown to improve acute kidney injury in rodent models. While alpha 7 nicotinic acetylcholine receptor (α7nAChR...

    Yasuna Nakamura, Hirotaka Matsumoto, Chia-Hsien Wu, Daichi Fukaya in Communications Biology (2023)

  7. No Access

    Article

    Immobilization of β-cyclodextrin onto polypropylene nonwoven fabric based on photooxidative surface modification

    We developed β-cyclodextrin (CD)/polypropylene (PP) composite nonwoven fabrics (NWFs) via surface modification of PP using the photoactivated chlorine dioxide radical (ClO2) oxidation method. The hydrophilicity ...

    Keita Yamamoto, Haruyasu Asahara, Maiko Moriguchi, Tsuyoshi Inoue in Polymer Journal (2023)

  8. Article

    Open Access

    Evaluation of oral care using MA-T gel for high-risk patients: a pilot study

    Oral care with gel is a common method for preventing aspiration in high-risk patients. An oral care gel is used to clean and moisturize the oral cavity. However, the effects of gel care on the oral bacteria re...

    Hitomi Ono-Minagi, Nao Gojo, Tsutomu Nohno, Tsuyoshi Inoue in BMC Oral Health (2023)

  9. Article

    Open Access

    Epoxidized graphene grid for highly efficient high-resolution cryoEM structural analysis

    Functionalization of graphene is one of the most important fundamental technologies in a wide variety of fields including industry and biochemistry. We have successfully achieved a novel oxidative modification...

    Junso Fujita, Fumiaki Makino, Haruyasu Asahara, Maiko Moriguchi in Scientific Reports (2023)

  10. No Access

    Chapter and Conference Paper

    Prediction of Instability in Rotating Shaft System with Casing by Operational Modal Analysis

    In recent years, as rotating machinery has become smaller and more efficient, various types of shaft vibration have become problems. Therefore, to prevent failures of rotating machinery, there is a growing nee...

    Daiki Goto, Tsuyoshi Inoue, Shogo Kimura in Advances in Mechanism and Machine Science (2023)

  11. Article

    Open Access

    Animal species identification utilising DNAs extracted from traditionally manufactured gelatin (Wanikawa)

    Gelatin, sourced from collagen, is an acid-, alkali- or enzymatically hydrolysed product obtained from animal skins and bones. Gelatin has been widely used for the manufacture of various cultural objects, e.g....

    Haruki Kuramata, Miho Hashiba, Yuriko Kai, Kazuhisa Nishizawa in Heritage Science (2022)

  12. Article

    Open Access

    A panel of nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants including Omicron

    We are amid the historic coronavirus infectious disease 2019 (COVID-19) pandemic. Imbalances in the accessibility of vaccines, medicines, and diagnostics among countries, regions, and populations, and those in...

    Ryota Maeda, Junso Fujita, Yoshinobu Konishi, Yasuhiro Kazuma in Communications Biology (2022)

  13. Article

    Open Access

    Neuroimmune system-mediated renal protection mechanisms

    The autonomic nervous system plays an important role in maintaining homeostasis in organisms. Recent studies have shown that it also controls inflammation by directly altering the function of the immune system...

    Tsuyoshi Inoue in Clinical and Experimental Nephrology (2021)

  14. Article

    Open Access

    Novel neutralizing human monoclonal antibodies against tetanus neurotoxin

    Tetanus is a fatal disease caused by tetanus neurotoxin (TeNT). TeNT is composed of a light chain (Lc) and a heavy chain, the latter of which is classified into two domains, N-terminus Hn and C-terminus Hc. Se...

    Takeharu Minamitani, Karin Kiyose, Ryota Otsubo, Toshihiro Ito in Scientific Reports (2021)

  15. Article

    Open Access

    Vagus nerve stimulation even after injury ameliorates cisplatin-induced nephropathy via reducing macrophage infiltration

    The efficacy of prior activation of an anti-inflammatory pathway called the cholinergic anti-inflammatory pathway (CAP) through vagus nerve stimulation (VNS) has been reported in renal ischemia-reperfusion inj...

    Rie Uni, Tsuyoshi Inoue, Yasuna Nakamura, Daichi Fukaya, Sho Hasegawa in Scientific Reports (2020)

  16. No Access

    Chapter

    Role of the Nervous System in Acute Kidney Injury

    Although its parasympathetic innervation has not been elucidated, the sympathetic innervation of the kidney is well studied. Renal sympathetic overactivity has been observed in essential hypertension and chron...

    Rie Uni, Chikara Abe, Reiko Inagi in Acute Kidney Injury and Regenerative Medic… (2020)

  17. No Access

    Article

    Adaptive feedforward cancellation with dam** control system in head positioning systems of HDDs

    Adaptive feedforward cancellation (AFC) with a dam** control system has been developed to improve the head-positioning accuracy in hard disk drives (HDDs). There are various disturbances that reduce the head...

    Shota Yabui, Tsuyoshi Inoue in Microsystem Technologies (2019)

  18. Article

    Adaptive feedforward cancellation with gain and dam** control system considering helium leakage in HDDs

    This study developed an adaptive feedforward cancellation system with gain and dam** control for hard disk drives (HDDs). The system was developed to compensate for fluid-induced vibration due to helium leak...

    Shota Yabui, Tsuyoshi Inoue in SN Applied Sciences (2019)

  19. No Access

    Article

    Order reduction and bifurcation analysis of a flexible rotor system supported by a full circular journal bearing

    Journal bearing has been widely used in the wide range of rotating machineries to support large loads and to add significant dam** to the system. Conventionally, its fluid film force is represented by the li...

    Hiroshi Kano, Mugen Ito, Tsuyoshi Inoue in Nonlinear Dynamics (2019)

  20. No Access

    Article

    Structure—activity relationship of porphyrin-induced photoinactivation with membrane function in bacteria and erythrocytes

    We analyzed the structure–activity relationship of porphyrins with the photoinactivation of membrane function in bacteria and erythrocytes. The porphyrins tested were protoporphyrin (PP), mesoporphyrin (MP), d...

    Hisato Kato, Keiko Komagoe, Tsuyoshi Inoue in Photochemical & Photobiological Sciences (2018)

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