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Clinical characteristics, outcomes and risk factors for mortality in hospitalized diabetes and chronic kidney disease patients after COVID-19 infection following widespread vaccination
COVID-19 poses a significant threat to patients with comorbidities, such as diabetes and chronic kidney disease (CKD). China experienced a nationwide COVID-19 endemic from December 2022 to January 2023, which ...
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Article
Contact Mechanics Response of Composite Cylindrical Roller Bearings Based on FEM
In response to the increasing demand for the working performance of cylindrical rollers in the industry, in this paper, PTFE and hollow cylindrical roller bearings are combined and improved to form composite c...
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Article
The Late Paleoproterozoic A-Type Granites in the Jiao-Liao-Ji Orogenic Belt, North China Craton: Petrogenesis and Implications for Post-Collision Extension
The Paleoproterozoic Jiao-Liao-Ji Orogenic Belt is a part of the Eastern Block, North China Craton. The Shuangcha rock mass has been recently recognized in Laohe group of Jiao-Liao-Ji Orogenic Belt, and it con...
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Article
Open AccessPTEN deficiency sensitizes endometrioid endometrial cancer to compound PARP-PI3K inhibition but not PARP inhibition as monotherapy
Poly (ADP-ribose) polymerase (PARP) inhibitors have emerged as promising cancer therapeutics especially for tumors with deficient homologous recombination (HR) repair. However, as HR-deficient tumors represent...
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Article
Proteomic modulation in breast tumors after metformin exposure: results from a “window of opportunity” trial
Reverse Phase Protein Array (RPPA) is a high-throughput antibody-based technique to assess cellular protein activity. The goal of this study was to assess protein marker changes by RPPA in tumor tissue from a ...
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Article
Increased plasma DPP4 activity predicts new-onset hypertension in Chinese over a 4-year period: possible associations with inflammation and oxidative stress
To investigate whether increased dipeptidyl peptidase 4 (DPP4) activity predicts new-onset hypertension in Chinese patients. A prospective study was conducted for 1884 adults (804 men/1080 women) aged 18–70 ye...
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Article
Open AccessMuscle-building supplement use and increased risk of testicular germ cell cancer in men from Connecticut and Massachusetts
No analytic epidemiological study has examined the relationship between use of muscle-building supplements (MBSs) and testicular germ cell cancer (TGCC) risk.
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Article
Open AccessSimilar blood-borne DNA methylation alterations in cancer and inflammatory diseases determined by subpopulation shifts in peripheral leukocytes
Although many DNA methylation (DNAm) alterations observed in peripheral whole blood/leukocytes and serum have been considered as potential diagnostic markers for cancer, their origin and their specificity for ...
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Article
Knockdown of the glucocorticoid receptor alters functional integration of newborn neurons in the adult hippocampus and impairs fear-motivated behavior
Glucocorticoids (GCs) secreted after stress reduce adult hippocampal neurogenesis, a process that has been implicated in cognitive aspects of psychopathology, amongst others. Yet, the exact role of the GC rece...
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Article
The N = 16 Spherical Shell Closure in 24O
The unbound excited states of the most neutron-rich dripline oxygen isotope, 24O, have been investigated by using the 24O(p,p′)24O* reaction at the beam energy of 62 MeV/nucleon in inverse kinematics. The first a...
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Article
Invariant Mass Spectroscopy of 23O via the (p, p′) Reaction in Inverse Kinematics
The neutron-rich oxygen isotope 23O has been investigated via proton inelastic scattering on a liquid hydrogen target at 63.5 MeV/nucleon. The invariant mass method in inverse kinematics was employed to reconstru...
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Article
Open AccessDiabetes and breast cancer risk: a meta-analysis
The potential of an increased risk of breast cancer in women with diabetes has been the subject of a great deal of recent research.
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Article
Efficient blue light generated by intracavity frequency doubling of a 937 nm Nd:GGG laser with BiB3O6
Efficient CW intracavity frequency doubling of a diode-end-pumped Nd:GGG laser operating on 4 F 3/2 → 4 I 9/2 transi...
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Article
Relationship of folate, vitamin B12 and methylation of insulin-like growth factor-II in maternal and cord blood
One of the speculated mechanisms underlying fetal origin hypothesis of breast cancer is the possible influence of maternal environment on epigenetic regulation, such as changes in DNA methylation of the insuli...
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Article
Optical Characterization of Iv-VI Mid-Infrared Vcsel
PbSe/PbSrSe multiple-quantum-well (MQW) structures and PbSrSe thin films were grown on BaF2 (111) substrates by molecular beam epitaxy (MBE) and characterized by Fourier transform infrared (FTIR) spectrometer. St...
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Article
Open AccessPortable stove use is associated with lower lung cancer mortality risk in lifetime smoky coal users
Domestic fuel combustion from cooking and heating, to which about 3 billion people worldwide are exposed, is associated with increased lung cancer risk. Lung cancer incidence in Xuanwei is the highest in China...
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Article
Variants in circadian genes and prostate cancer risk: a population-based study in China
Circadian genes influence a variety of biological processes that are important in prostate tumorigenesis including metabolism. To determine if variants in circadian genes alter prostate cancer risk, we genotyp...
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Article
An effective intermediate Al/Au electrode for stacked color-tunable organic light emitting devices
Bright and efficient stacked color-tunable organic light emitting devices (OLEDs) using an intermediate Al/Au electrode have been reported. The effects of the thicknesses of Al and Au layers on the luminance c...
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Article
Characterisation of two enteroviruses isolated from Australian brushtail possums (Trichosurus vulpecula) in New Zealand
Two enteroviruses, designated W1 and W6, were isolated from intestinal contents of Australian brushtail possums (Trichosurus vulpecula) in New Zealand. The genomic sequences of W1 and W6 were 7390 and 7391 nucleo...
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Article
A Petrov-Galerkin method for a singularly perturbed ordinary differential equation with non-smooth data
In this paper, a singularly perturbed ordinary differential equation with non-smooth data is considered. The numerical method is generated by means of a Petrov-Galerkin finite element method with the piecewise...