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Article
The Influence of the Synthetic Organoselenium Preparation 974zh on the Immunogenic Activity of Yersinia pestis EV Vaccine Strain NIIEG
In the present study, a stimulating effect of a new synthetic organoselenium compound 2,6-dipyridinium-9-selenabicyclo[3.3.1]nonandibromide (974zh) on the immunogenic activity of the vaccine strain Yersinia pesti...
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Article
pH-Sensitive Paramagnetic Probe 4-(Methylamino)-2-Ethyl-5,5-Dimethyl-4-Pyridine-2-Yl-2,5-Dihydro-1H-Imidazol-1-Oxyl for Controlling Microacidity Inside Poly-D,L-Lactide Films during Degradation In Vitro
Monitoring of the acidity inside the pores of aliphatic polyesters during their swelling and hydrolysis is important challenge of biomedicine. pH-sensitive nitroxyl radical 5,5-dimetyl- 4-dimetylamino-2-ethyl-...
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Article
The Diffusion of TEMPONE Radical in the Graft Copolymer of N-Isopropylacrylamide with Oligolactide in the Presence of Supercritical Carbon Dioxide by In Situ EPR Method
Impregnation of the thermoresponsive graft copolymer of N-isopropylacrylamide and oligolactide, (P(NIPAM-co-PLA)), with the composition 83.8 : 16.2 wt % with a stable nitroxyl radical, 4-oxo-2,2,6,6-tetramethyl-p...
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Article
Aliphatic Polyesters for Biomedical Purposes: Design and Kinetic Regularities of Degradation in vitro
This paper presents a brief review of the methods for creating and diagnosing materials based on aliphatic polyesters used to create temporary prostheses and dosage forms of prolonged action. After a review of...
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Article
Kinetics of Release of a Bifunctional 2,2,5,5-Tetramethyl-4-Phenyl-3-Imidazoline-1-Oxyl-3-Oxide Probe from Poly-D,L-Lactide Films Formed Using Supercritical Carbon Dioxide
Optical spectroscopy and ESR spectroscopy were used for the first time to quantitatively describe the release of a nitroxyl probe from poly-D,L-lactide (PDLLA) films into phosphate buffer. The bifunctional pro...
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Article
Estimation of an Inertia Tensor and Automatic Balancing of a Microsatellite Mockup on an Air-Bearing Testbed
This paper considers the problem of determining the position of the center-of-mass and inertia tensor of a microsatellite mockup on an air-bearing testbed by using optical measurements. The position of the moc...
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Article
Comparative Analysis of MPTP Neurotoxicity in Mice with a Constitutive Knockout of the α-Synuclein Gene
Aggregated forms of α-synuclein are core components of pathohistological inclusions known as Lewy bodies in substantia nigra (SN) neurons of patients with Parkinson’s disease (PD). The role of α-synuclein in s...
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Article
Modeling a Nanosatellite’s Angular Motion Dam** Using a Hysteresis Plate
The angular motion of a CubeSat-type nanosatellite with a passive magnetic attitude control system is mathematically modelled. The attitude control system consists of a permanent magnet and hysteresis dampers ...
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Article
Immunotropic Properties of an Experimental Synthetic Selenium-Organic Compound
We studied immunotropic properties of synthetic selenium-organic preparation 2,6-dipyridinium-9-selenabicyclo[3.3.1]nonyl dibromide (974zh). The experimental preparation reduced the cAMP/cGMP ratio, which indi...
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Article
Kinetics of Release of the TEMPONE Nitroxyl Radical from Poly-D,L-Lactide Foamed in the Supercritical Carbon Dioxide Medium
Abstract—The electron spin resonance method was used to quantitatively describe the release of a paramagnetic bioactive substance from a biodegradable polymer matrix. A standard spin probe TEMPONE was chosen as t...
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Article
Effect of Synthetic Organoselenium Drug on the Degree of Pathological Changes in the Organs of White Mice Immunized with Tularemia and Brucellosis Vaccines
We studied the effect of the organoselenium compound 2,6-dipyridinium-9-selenium-bicyclo[ 3,3,1]nonan dibromide (974zh) on the severity of pathological changes in the organs of experimental animals immunized w...
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Article
Features of the Magnetic Properties of the [Fe(salen)(2-Me-Him)]n Chain Structure
The iron(III) compound of composition [Fe(III)(salen)(2-Me-Him)]n, where H2salen = N, N′-ethylenebis(salicylaldimine) and 2-Me-Him = 2-methylimidazolate bridging ligand, was prepared. Magnetic resonance and magne...
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Chapter
The Unique Spectrum of Mutations in Patients with Hereditary Tyrosinemia Type 1 in Different Regions of the Russian Federation
Background: Hereditary tyrosinemia (HT1) is an autosomal recessive disorder characterized by impaired tyrosine catabolism because of fumarylacetoacetate hydrolase deficiency. HT1 is caused by homozygous or compo...
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Article
EPR Diagnostics of D,L-Polylactide Porous Matrices Formed in Supercritical CO2
The regularities of formation of D,L-polylactide porous matrices in supercritical CO2 environment with simultaneous impregnation with paramagnetic biologically active 4-hydroxy-2,2,6,6-tetramethylpiperidine- 1-ox...
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Article
Pure Yang–Mills Solutions on dS4
We consider pure SU(2) Yang–Mills theory on four-dimensional de Sitter space dS4 and construct smooth and spatially homogeneous classical Yang–Mills fields. Slicing dS4 as
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Article
Properties of [Fe(Salten)Cl] Being a Precursor for Spin-Crossover Compounds in Polycrystals and Vitrified Acetonitrile Solutions
The complexes of precursor with pentadentate Salten ligand has been shown to have high-spin state (S = 5/2) in a single crystal and polycrystalline phase and contain both high-spin and low-spin (S = 1/2) fraction...
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Article
To the Precision of Measuring Concentrations of Nitroxide Radicals in Polymers by EPR Technique
The precision of measuring concentrations of nirtoxide radicals in polymeric matrixes using modern electron paramagnetic resonance spectrometer is analyzed. The contributions of the radical nature and concentr...
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Article
Open AccessHeadache and pregnancy: a systematic review
This systematic review summarizes the existing data on headache and pregnancy with a scope on clinical headache phenotypes, treatment of headaches in pregnancy and effects of headache medications on the child ...
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Article
Intermolecular interactions and spin states of complexes [Fe(3-MeO-Qsal)2]Y (Y = PF6, BF4)
Compounds [Fe(3-MeO-Qsal)2]Y (Y = PF6, BF4) have been prepared by diffusion method and studied in temperature range 5–300 K by EPR and magnetic susceptibility methods. The coexistence of spatially separated high-...
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Article
Enhancing multipurpose use of cow-parsnip in processing of gold-bearing sulfides
The authors consider variants of multipurpose use of plant materials—ground green mass of Sosnovsky cow-parsnip. Simultaneous production of aqueous extract possessing depression properties and post-extraction ...
