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Chapter and Conference Paper
Impact of Gradual Vascular Deformations on the Intra-aneurysmal Hemodynamics
The treatment of intracranial aneurysms based on stentassisted coiling often leads to local vascular deformations. Patient-specific data of an aneurysm in the pre interventional and follow-up state is used to ...
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Chapter and Conference Paper
Computer-aided Detection of the Most Suitable MRI Sequences for Subsequent Spinal Metastasis Delineation
Detection and segmentation of vertebral metastases is a crucial step for support of diagnosis and treatment planning, especially in minimally invasive interventions. Even though computer-assistant tools will n...
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Chapter and Conference Paper
Two-Step Trajectory Visualization for Robot-Assisted Spine Radiofrequency Ablations
Radiofrequency Ablations (RFAs) can be employed for the treatment of spine metastases. Instruments are therefor inserted through the vertebra’s pedicle into cancerous tissue within the vertebral body. This req...
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Article
Semiautomatic neck curve reconstruction for intracranial aneurysm rupture risk assessment based on morphological parameters
Morphological parameters of intracranial aneurysms (IAs) are well established for rupture risk assessment. However, a manual measurement is error-prone, not reproducible and cumbersome. For an automatic extrac...
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Article
Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): Phase I: Segmentation
Advanced morphology analysis and image-based hemodynamic simulations are increasingly used to assess the rupture risk of intracranial aneurysms (IAs). However, the accuracy of those results strongly depends on...
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Chapter and Conference Paper
Towards Automated Reporting and Visualization of Lymph Node Metastases of Lung Cancer
For lung cancer staging, the involvement of lymph nodes in the mediastinum, meaning along the trachea and bronchi, has to be assessed. Depending on the staging results, treatment options include radiation ther...
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Chapter and Conference Paper
Segmentation of Vertebral Metastases in MRI Using an U-Net like Convolutional Neural Network
This study’s objective was to segment vertebral metastases in diagnostic MR images by using a deep learning-based approach. Segmentation of such lesions can present a pivotal step towards enhanced therapy plan...
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Article
Open AccessMultiple Aneurysms AnaTomy CHallenge 2018 (MATCH): uncertainty quantification of geometric rupture risk parameters
Geometric parameters have been proposed for prediction of cerebral aneurysm rupture risk. Predicting the rupture risk for incidentally detected unruptured aneurysms could help clinicians in their treatment dec...
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Article
Suitability of intravascular imaging for assessment of cerebrovascular diseases
Arteriosclerosis of the vascular system is associated with many accompanying diseases. Especially cerebral arteriosclerosis is a main risk factor for ischemic strokes. We want to verify the practicability of i...
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Article
Flow-splitting-based computation of outlet boundary conditions for improved cerebrovascular simulation in multiple intracranial aneurysms
Image-based hemodynamic simulations have great potential for precise blood flow predictions in intracranial aneurysms. Due to model assumptions and simplifications with respect to boundary conditions, clinical...
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Article
Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH)—phase II: rupture risk assessment
Assessing the rupture probability of intracranial aneurysms (IAs) remains challenging. Therefore, hemodynamic simulations are increasingly applied toward supporting physicians during treatment planning. Howeve...
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Chapter and Conference Paper
VICTORIA
For the characterization of intracranial aneurysms, morphological and hemodynamic parameters provide valuable information. To evaluate these quantities, the separation of the aneurysm from its parent vessel is...
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Article
Interactive exploration of a 3D intracranial aneurysm wall model extracted from histologic slices
Currently no detailed in vivo imaging of the intracranial vessel wall exists. Ex vivo histologic images can provide information about the intracranial aneurysm (IA) wall composition that is useful for the unde...
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Article
Open AccessCombining visual analytics and case-based reasoning for rupture risk assessment of intracranial aneurysms
Medical case-based reasoning solves problems by applying experience gained from the outcome of previous treatments of the same kind. Particularly for complex treatment decisions, for example, incidentally foun...
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Article
Open AccessMultimodal validation of focal enhancement in intracranial aneurysms as a surrogate marker for aneurysm instability
Circumferential enhancement on MR vessel wall imaging has been proposed as a biomarker of a higher risk of rupture in intracranial aneurysms. Focal enhancement is frequently encountered in unruptured aneurysms...
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Chapter and Conference Paper
Interactive Visualization of Cerebral Blood Flow for Arteriovenous Malformation Embolisation
Arteriovenous malformations in the brain are abnormal connections between cerebral arteries and veins without the capillary system. They might rupture with fatal consequences. Their treatment is highly patient...
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Chapter and Conference Paper
A Machine Learning Approach Towards Fatty Liver Disease Detection in Liver Ultrasound Images
Fatty liver disease (FLD) is one of the prominent diseases which affects the normal functionality of the liver by building vacuoles of fat in the liver cells. FLD is an indicator of imbalance in the metabolic ...
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Chapter and Conference Paper
Towards Deep Learning-based Wall Shear Stress Prediction for Intracranial Aneurysms
This work aims at a deep learning-based prediction of wall shear stresses (WSS) for intracranial aneurysms. Based on real patient cases, we created artificial surface models of bifurcation aneurysms. After sim...
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Article
Open AccessComplex wall modeling for hemodynamic simulations of intracranial aneurysms based on histologic images
For the evaluation and rupture risk assessment of intracranial aneurysms, clinical, morphological and hemodynamic parameters are analyzed. The reliability of intracranial hemodynamic simulations strongly depen...
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Article
Open AccessDistance and force visualisations for improved simulation of intracranial aneurysm clip**
The treatment of cerebral aneurysms shifted from microsurgical to endovascular therapy. But for some difficult aneurysm configurations, e.g. wide neck aneurysms, microsurgical clip** is better suited. From t...
