42 Result(s)
within
Shu-yang **ang
Science, Humanities and Social Sciences, multidisciplinary
English
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Article
Open AccessPhosphoglycerate kinase 1 acts as a cargo adaptor to promote EGFR transport to the lysosome
The epidermal growth factor receptor (EGFR) plays important roles in multiple cellular events, including growth, differentiation, and motility. A major mechanism of downregulating EGFR function involves its en...
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Article
Open AccessApproaching expert-level accuracy for differentiating ACL tear types on MRI with deep learning
Treatment for anterior cruciate ligament (ACL) tears depends on the condition of the ligament. We aimed to identify different tear statuses from preoperative MRI using deep learning-based radiomics with sex an...
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Article
Open AccessALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation
Amyotrophic lateral sclerosis (ALS) is a severely debilitating neurodegenerative condition that is part of the same disease spectrum as frontotemporal dementia (FTD). Mutations in the CCNF gene, encoding cyclin F...
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Article
Open AccessPrognostic impact of blood urea nitrogen to albumin ratio on patients with sepsis: a retrospective cohort study
To investigate the ability of the ratio of blood urea nitrogen (BUN) to serum albumin ratio (BAR) in patients with sepsis in intensive care units (ICUs) to predict the prognosis of short-and long-term death. D...
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Article
Autonomous self-burying seed carriers for aerial seeding
Aerial seeding can quickly cover large and physically inaccessible areas1 to improve soil quality and scavenge residual nitrogen in agriculture2, and for postfire reforestation3–5 and wildland restoration6,7. How...
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Open AccessOn the origin of elasticity and heat conduction anisotropy of liquid crystal elastomers at gigahertz frequencies
Liquid crystal elastomers that offer exceptional load-deformation response at low frequencies often require consideration of the mechanical anisotropy only along the two symmetry directions. However, emerging ...
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Open AccessGenomic analyses of 10,376 individuals in the Westlake BioBank for Chinese (WBBC) pilot project
We initiate the Westlake BioBank for Chinese (WBBC) pilot project with 4,535 whole-genome sequencing (WGS) individuals and 5,841 high-density genoty** individuals, and identify 81.5 million SNPs and INDELs, ...
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Open AccessMetagenomic sequencing for detection and identification of the boxwood blight pathogen Calonectria pseudonaviculata
Pathogen detection and identification are key elements in outbreak control of human, animal, and plant diseases. Since many fungal plant pathogens cause similar symptoms, are difficult to distinguish morpholog...
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Open AccessSerum anti-SERPINE1 antibody as a potential biomarker of acute cerebral infarction
The presence of disease-specific antigens and autoantibodies in the sera of patients with atherosclerosis-related diseases has been widely reported and is considered to result from inflammation of the arterial...
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Open AccessAerodynamics-assisted, efficient and scalable kirigami fog collectors
To address the global water shortage crisis, one of the promising solutions is to collect freshwater from the environmental resources such as fog. However, the efficiency of conventional fog collectors remains...
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Article
Open AccessSerum glial fibrillary acidic protein and S100 calcium-binding protein B correlates cerebral vessel reactivity following carotid artery stenting
Using detection markers in serum has the advantages of simplicity, repeatability and the capability. This study combined the use of serum glial fibrillary acidic protein (GFAP) and S100B protein (S100B) with i...
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Open AccessSerum anti-AP3D1 antibodies are risk factors for acute ischemic stroke related with atherosclerosis
Atherosclerosis has been considered as the main cause of morbidity, mortality, and disability worldwide. The first screening for antigen markers was conducted using the serological identification of antigens b...
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Article
Open AccessSETD4-expressing cells contribute to pancreatic development and response to cerulein induced pancreatitis injury
In the adult pancreas, the presence of progenitor or stem cells and their potential involvement in homeostasis and regeneration remains unclear. Here, we identify that SET domain-containing protein 4 (SETD4), ...
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Open AccessSetd4 controlled quiescent c-Kit+ cells contribute to cardiac neovascularization of capillaries beyond activation
Blood vessels in the adult mammal exist in a highly organized and stable state. In the ischemic heart, limited expansion capacity of the myocardial vascular bed cannot satisfy demands for oxygen supply and the...
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Article
Open AccessTherapeutic effects and prognostic factors of 125I brachytherapy for pelvic recurrence after early cervical cancer surgery
To investigate the efficacy of 125I seed implantation in the treatment regimen of pelvic recurrence after early cervical cancer surgery and to analyse prognostic factors. To evaluate efficacy and analyse prognost...
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Open AccessKnocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth
The protein alpha-synuclein (α-syn) is unusual because, depending on its conformation and the type of cell in which it is expressed, it is pro-death or pro-survival, triggering neurodegeneration in Parkinson’s...
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Article
Open AccessNeuroendocrine prostate cancer has distinctive, non-prostatic HOX code that is represented by the loss of HOXB13 expression
HOX gene-encoded homeobox proteins control body patterning during embryonic development; the specific expression pattern of HOX genes may correspond to tissue identity. In this study, using RNAseq data of 1019...
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Article
Author Correction: Molecular heterogeneity drives reconfigurable nematic liquid crystal drops
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessSpatiotemporal dynamics of hemorrhagic fever with renal syndrome in Jiangxi province, China
Historically, Jiangxi province has had the largest HFRS burden in China. However, thus far, the comprehensive understanding of the spatiotemporal distributions of HFRS is limited in Jiangxi. In this study, sea...
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Open AccessThe physical significance of acoustic parameters and its clinical significance of dysarthria in Parkinson’s disease
Dysarthria is universal in Parkinson’s disease (PD) during disease progression; however, the quality of vocalization changes is often ignored. Furthermore, the role of changes in the acoustic parameters of pho...
