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Article
Uncovering the Interaction Interface Between Harpin (Hpa1) and Rice Aquaporin (OsPIP1;3) Through Protein–Protein Docking: An In Silico Approach
Hpa1 (a type of harpin) is involved in T3SS (Type III Secretion System) assembly in the infection mechanism by Xanthomonas Oryzae pv. oryzae (Xoo). Hpa1 interacts with the plasma membrane components of plants the...
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Chapter and Conference Paper
E-Learning Paradigm in Cloud Computing and Pertinent Challenges in Models Used for Cloud Deployment
The pedagogical science has improved immensely in each section of learning and education due to adoption of recent developments in Information and Communication Technologies (ICT) domain. Adopting web-based to...
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Chapter and Conference Paper
Single and Multi-material Topology Optimization of Continuum Structures: ABAQUS Plugin
This research addresses the need for versatile topology optimization techniques capable of optimizing both single and multi-material designs. The extended Python code incorporates the modified Bi directional E...
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Article
Open AccessTargeting allosteric binding site in methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) to identify natural product inhibitors via structure-based computational approach
Cancer has been viewed as one of the deadliest diseases worldwide. Among various types of cancer, breast cancer is the most common type of cancer in women. Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) is...
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Article
Open AccessA Paradigm Shift from International to Transnational Medical Education
In recent years, the number of medical students seeking international opportunities has grown. To satisfy these demands, collaborative international programs have been developed. However, the benefits of these...
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Article
Structural differences in 3C-like protease (Mpro) from SARS-CoV and SARS-CoV-2: molecular insights revealed by Molecular Dynamics Simulations
Novel coronavirus SARS-CoV-2 has infected millions of people with thousands of mortalities globally. The main protease (Mpro) is vital in processing replicase polyproteins. Both the CoV’s Mpro shares 97% ident...
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Article
Mechanical and microstructural behavior of high strength geopolymer concrete inclusion of various industrial wastes
The experimental work is intended to identify the mix proportion of M100 grade of High-Strength Geopolymer Concrete (HSGPC) by a targeted strength-based method. Concrete ingredients are Ground Granulated Blast...
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Article
Experimental investigation on mechanical properties of ternary blended concrete using manufactured sand
In this study, ordinary Portland cement was replaced with different industrial by-products such as ground-granulated blast-furnace slag (GGBFS) and microfine (MF) with a fraction of 0%, 10%, 20%, 30%, 40%, 50%...
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Article
Experimentation with the EDM parameter through a full factorial technique and optimization using regression analysis with carbon nanotubes
Using an unconventional method of machining, electric discharge machining is capable of processing extremely hard materials that are inaccessible to more traditional machining methods. Electric discharge machi...
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Chapter and Conference Paper
A Comparison of the Key Size and Security Level of the ECC and RSA Algorithms with a Focus on Cloud/Fog Computing
The rapid development of data generation and demand for real-time processing and analysis in the Internet of Things (IoT) has led to the emergence of new issues. In response, an extension of cloud computing, k...
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Chapter and Conference Paper
Numerical Synthesis of Bending Behaviour of Flexible Composite Tape Spring
The tape spring is defined as a straight, thin-walled elastic strip with a curved cross section. It has inherent properties which allow for folding elastically, and when unfolded, it releases stored energy. In...
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Article
Designing multi-epitope based peptide vaccine targeting spike protein SARS-CoV-2 B1.1.529 (Omicron) variant using computational approaches
Millions of lives have been infected since the SARS-CoV-2 outbreak in 2019. The high human-to-human transmission rate has warranted a need for a vaccine to protect people. Although some vaccines are in use, du...
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Article
In-Vivo and Ex-Vivo Brain Uptake Studies of Peptidomimetic Neurolysin Activators in Healthy and Stroke Animals
Neurolysin (Nln) is a peptidase that functions to preserve the brain following ischemic stroke by hydrolyzing various neuropeptides. Nln activation has emerged as an attractive drug discovery target for treatm...
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Article
Optimization of production parameter and application of glycoprotein produced from Sphingobacterium thalpophilum DP9
Biosurfactants are biologically secreted amphiphilic molecules which resemble with the chemical surfactant in function. Compared to the chemical surfactants, they are biodegradable, biocompatible and less toxi...
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Chapter and Conference Paper
Experimental Investigation on Geopolymer Concrete Containing Recycled Plastic Waste Aggregates
The increasing rate of plastic waste generated in the world day by day is alarming for humans. The illegal burning plastic waste result into the releasing of hydrocarbons is stringent pollutants. The amount of...
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Chapter and Conference Paper
Utilization of GGBFS and Micro-fine as Partial Replacement of Cement in Mortar with Manufactured and River Sand
The compressive strength behavior of cement mortar with ground granulated blast furnace slag (GGBFS) and micro-fine (ultrafine GGBFS) was investigated. The strength characteristics of cement mortar are examine...
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Chapter and Conference Paper
Experimental Study on the Performance of Manufactured Sand Over Natural Sand-Based Cement Mortar
In the current construction industry, due to rapid changes in construction activities, the availability of natural sand has been exhausted. In addition, it may be necessary to transport high-quality sand from ...
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Chapter and Conference Paper
Experimental Investigation on Development of Compressive Strength of High-Strength Geopolymer Concrete Containing M-Sand
The serious issue related to more consumption of cement-based concrete because of the CO2 emission, while manufacturing of the cement. The Portland cement manufacturing causes the emissions of pollutants in atmos...
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Article
Pearson Correlation Coefficient-based performance enhancement of Vanilla Neural Network for stock trend prediction
The prediction of a volatile stock market is a challenging task. While various neural networks are integrated to address stock trend prediction problems, the weight initialization of such networks plays a cruc...
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Article
Open AccessKnocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth
The protein alpha-synuclein (α-syn) is unusual because, depending on its conformation and the type of cell in which it is expressed, it is pro-death or pro-survival, triggering neurodegeneration in Parkinson’s...
