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Article
Open AccessCo-localization of antibiotic resistance genes is widespread in the infant gut microbiome and associates with an immature gut microbial composition
In environmental bacteria, the selective advantage of antibiotic resistance genes (ARGs) can be increased through co-localization with genes such as other ARGs, biocide resistance genes, metal resistance genes...
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Article
Open AccessThe airway microbiota of neonates colonized with asthma-associated pathogenic bacteria
Culture techniques have associated colonization with pathogenic bacteria in the airways of neonates with later risk of childhood asthma, whereas more recent studies utilizing sequencing techniques have shown t...
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Article
Open AccessExpanding known viral diversity in the healthy infant gut
The gut microbiome is shaped through infancy and impacts the maturation of the immune system, thus protecting against chronic disease later in life. Phages, or viruses that infect bacteria, modulate bacterial ...
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Article
Open AccessGenome binning of viral entities from bulk metagenomics data
Despite the accelerating number of uncultivated virus sequences discovered in metagenomics and their apparent importance for health and disease, the human gut virome and its interactions with bacteria in the g...
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Article
Open AccessPrenatal dietary supplements influence the infant airway microbiota in a randomized factorial clinical trial
Maternal dietary interventions during pregnancy with fish oil and high dose vitamin D have been shown to reduce the incidence of asthma and wheeze in offspring, potentially through microbial effects in pregnan...
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Article
Open AccessVirulent coliphages in 1-year-old children fecal samples are fewer, but more infectious than temperate coliphages
Bacteriophages constitute an important part of the human gut microbiota, but their impact on this community is largely unknown. Here, we cultivate temperate phages produced by 900 E. coli strains isolated from 64...
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Article
Open AccessGenomic analysis of Acidianus hospitalis W1 a host for studying crenarchaeal virus and plasmid life cycles
The Acidianus hospitalis W1 genome consists of a minimally sized chromosome of about 2.13 Mb and a conjugative plasmid pAH1 and it is a host for the model filamentous lipothrixvirus AFV1. The chromosome carries t...
