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Article
Open AccessHigh throughput platform technology for rapid target identification in personalized phage therapy
As bacteriophages continue to gain regulatory approval for personalized human therapy against antibiotic-resistant infections, there is a need for transformative technologies for rapid target identification th...
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Article
Open AccessVirulent coliphages in 1-year-old children fecal samples are fewer, but more infectious than temperate coliphages
Bacteriophages constitute an important part of the human gut microbiota, but their impact on this community is largely unknown. Here, we cultivate temperate phages produced by 900 E. coli strains isolated from 64...
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Article
Open Access7-Deazaguanine modifications protect phage DNA from host restriction systems
Genome modifications are central components of the continuous arms race between viruses and their hosts. The archaeosine base (G+), which was thought to be found only in archaeal tRNAs, was recently detected in g...
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Article
A proposed new bacteriophage subfamily: “Jerseyvirinae”
Based on morphology and comparative nucleotide and protein sequence analysis, a new subfamily of the family Siphoviridae is proposed, named “Jerseyvirinae” and consisting of three genera, “Jerseylikevirus”, “Sp3u...
