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  1. No Access

    Article

    Prophylactic effects of cucurbitacin B in the EAE Model of multiple sclerosis by adjustment of STAT3/IL-23/IL-17 axis and improvement of neuropsychological symptoms

    Multiple sclerosis (MS) is an autoimmune disease that affects the central nervous system. Although remarkable progress has been made in treating MS, current therapies are less effective in protecting against t...

    Samaneh Reiszadeh-Jahromi, Mohammad Haddadi, Pegah Mousavi… in Metabolic Brain Disease (2022)

  2. No Access

    Article

    Sepantronium Bromide (YM155), A Small Molecule Survivin Inhibitor, Promotes Apoptosis by Induction of Oxidative Stress, Worsens the Behavioral Deficits and Develops an Early Model of Toxic Demyelination: In Vivo and In-Silico Study

    Cuprizone (cup) model targets oligodendrocytes (OLGs) degeneration and is frequently used for the mechanistic understanding of de- and remyelination. Improperly, this classic model is time-consuming and the ex...

    Samaneh Reiszadeh-Jahromi, Mohammad-Reza Sepand… in Neurochemical Research (2019)

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    Article

    Neuroprotective Effect of Decalepis hamiltonii in Paraquat-Induced Neurotoxicity in Drosophila melanogaster: Biochemical and Behavioral Evidences

    In this paper, we have demonstrated for the first time, the antioxidant and neuroprotective effects of Decalepis hamiltonii (Dh) root extract against paraquat (PQ)-induced oxidative stress and neu...

    Samaneh Reiszadeh Jahromi, Mohammad Haddadi, T. Shivanandappa… in Neurochemical Research (2013)