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Article
Open AccessPotential efficacy of digital polymerase chain reaction for non-invasive prenatal screening of autosomal aneuploidies: a systematic review and meta-analysis
Digital Polymerase Chain Reaction (dPCR) presents a promising approach for quantifying DNA and analyzing copy number variants, particularly in non-invasive prenatal testing. This method offers a streamlined an...
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Article
Prediction of bleeding in placenta accrete spectrum with lacunar surface: a novel aspect
Diagnosing the placenta accreta spectrum is crucial to prevent morbidities and mortalities among women with the suspicion of this pathology. We aim to evaluate novel ultrasonography markers for these patients ...
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Article
Open AccessPrevailing of HPV-16 and 52 genotype in 2022–2023 in Sanandaj, Iran
Human papillomavirus (HPV) presents a potential threat to the onset of carcinogenesis in the cervix, anogenital regions, and oropharynx. HPV encompasses over 200 types, with at least 12 having the potential t...
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Article
Breast Implant Illness as a Challenging Disorder in Clinics
Breast augmentation is a common cosmetic procedure but may cause physical and psychological side effects, including malignancies and breast implant illness (BII). BII is a condition that can improve with impla...
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Article
Differential dysregulation of CREB and synaptic genes in transgenic Drosophila melanogaster expressing shaggy (GSK3), TauWT, or Amyloid-beta
Tau, Amyloid-beta (Aβ42), and Glycogen synthase kinase 3 (GSK3) contribute to synaptic dysfunction observed in Alzheimer's disease (AD), the most common form of dementia. In the current study, the effect of pan-n...
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Article
Potential of whey protein as a nutritional intervention in alleviating manganese and paraquat-mediated oxidative stress in Apis mellifera meda
The role of nutrition in alleviating the physiological disorders caused by toxicants in honeybees is currently receiving considerable attention. This study aimed to determine whether dietary supplementation wi...
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Article
Prophylactic effects of cucurbitacin B in the EAE Model of multiple sclerosis by adjustment of STAT3/IL-23/IL-17 axis and improvement of neuropsychological symptoms
Multiple sclerosis (MS) is an autoimmune disease that affects the central nervous system. Although remarkable progress has been made in treating MS, current therapies are less effective in protecting against t...
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How Prevalent Is Cancer in Confirmed Cases with Coronaviruses and Severe Acute Respiratory Syndromes?
Novel coronavirus disease 2019 (COVID-19) has posed a crucial hazard to global health. The new species share similarities with the two previously emerged entities: severe acute respiratory syndrome (SARS) and ...
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Article
Biochemical and Behavioral Evaluation of Human MAPT Mutations in Transgenic Drosophila melanogaster
Mutations in the human microtubule-associated protein tau (hMAPT) gene including R406W and V337M result in autosomal dominant neurodegenerative disorder. These mutations lead to hyperphosphorylation and aggregati...
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Article
Neuroprotective Effect of Decalepis hamiltonii in Paraquat-Induced Neurotoxicity in Drosophila melanogaster: Biochemical and Behavioral Evidences
In this paper, we have demonstrated for the first time, the antioxidant and neuroprotective effects of Decalepis hamiltonii (Dh) root extract against paraquat (PQ)-induced oxidative stress and neu...
