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  1. Article

    Retraction Note: p14ARF promotes RB accumulation through inhibition of its Tip60-dependent acetylation

    C. Leduc, P. Claverie, B. Eymin, E. Col, S. Khochbin, E. Brambilla, S. Gazzeri in Oncogene (2023)

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  2. Article

    Correction to: p14ARF inhibits the growth of lung adenocarcinoma cells harbouring an EGFR L858R mutation by activating a STAT3-dependent pro-apoptotic signalling pathway

    A Correction to this paper has been published: https://doi.org/10.1038/s41388-021-01653-4

    P. Ozenne, D. Dayde, E. Brambilla, B. Eymin, S. Gazzeri in Oncogene (2021)

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    Article

    Nuclear trafficking of EGFR by Vps34 represses Arf expression to promote lung tumor cell survival

    Epidermal growth factor receptor (EGFR) is a cell surface receptor that has an essential role in cell proliferation and survival, and overexpression of EGFR is a common feature of human cancers. In Non-small-c...

    D Dayde, M Guerard, P Perron, A-S Hatat, C Barrial, B Eymin, S Gazzeri in Oncogene (2016)

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    Article

    p14ARF inhibits the growth of lung adenocarcinoma cells harbouring an EGFR L858R mutation by activating a STAT3-dependent pro-apoptotic signalling pathway

    Epidermal growth factor receptor (EGFR) stimulates proliferative and survival signals. Activating mutations of EGFR are involved in the aetiology and maintenance of the malignant phenotype of lung tumours. We ...

    P Ozenne, D Dayde, E Brambilla, B Eymin, S Gazzeri in Oncogene (2013)

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    Article

    Sumoylation of ING2 regulates the transcription mediated by Sin3A

    ING2 (inhibitor of growth 2) is a candidate tumor-suppressor gene involved in cell cycle control, apoptosis and senescence. Although the functions of ING2 within the chromatin remodeling complex Sin3A/histone ...

    D Ythier, D Larrieu, R Binet, O Binda, C Brambilla, S Gazzeri, R Pedeux in Oncogene (2010)

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    Article

    The transcription factor E2F1 and the SR protein SC35 control the ratio of pro-angiogenic versus antiangiogenic isoforms of vascular endothelial growth factor-A to inhibit neovascularization in vivo

    The transcription factor E2F1 has a crucial role in the control of cell growth and has been shown to regulate neoangiogenesis in a p53-dependent manner through inhibition of activity of the VEGF-A (vascular en...

    G Merdzhanova, S Gout, M Keramidas, V Edmond, J-L Coll, C Brambilla… in Oncogene (2010)

  7. Article

    E2F1 controls alternative splicing pattern of genes involved in apoptosis through upregulation of the splicing factor SC35

    The transcription factor E2F1 has a key function during S phase progression and apoptosis. It has been well-demonstrated that the apoptotic function of E2F1 involves its ability to transactivate pro-apoptotic ...

    G Merdzhanova, V Edmond, S De Seranno, A Van den Broeck… in Cell Death & Differentiation (2008)

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    Article

    E2F-1, Skp2 and cyclin E oncoproteins are upregulated and directly correlated in high-grade neuroendocrine lung tumors

    The transcription factor E2F-1 plays a crucial role in the control of cellular growth. We previously reported its differential pattern of expression in human lung tumors. In this study, we have investigated th...

    C Salon, G Merdzhanova, C Brambilla, E Brambilla, S Gazzeri, B Eymin in Oncogene (2007)

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    Article

    Human tumor suppressor p14ARF negatively regulates rRNA transcription and inhibits UBF1 transcription factor phosphorylation

    The nucleolar Arf protein has been shown to regulate cell cycle through both p53-dependent and -independent pathways. In addition to the well-characterized Arf-mdm2-p53 pathway, several partners of Arf have re...

    O Ayrault, L Andrique, D Fauvin, B Eymin, S Gazzeri, P Séité in Oncogene (2006)

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    Article

    RETRACTED ARTICLE: p14ARF promotes RB accumulation through inhibition of its Tip60-dependent acetylation

    p14ARF is a tumour suppressor which plays a critical role in p53-dependent or -independent cell growth control. Several studies have recently provided evidence that p14ARF can also interfere either directly or in...

    C Leduc, P Claverie, B Eymin, E Col, S Khochbin, E Brambilla, S Gazzeri in Oncogene (2006)

  11. Article

    E2F1 induces apoptosis and sensitizes human lung adenocarcinoma cells to death-receptor-mediated apoptosis through specific downregulation of c-FLIPshort

    E2F1 is a transcription factor that plays a well-documented role during S phase progression and apoptosis. We had previously postulated that the low level of E2F1 in primary lung adenocarcinoma contributes to ...

    C Salon, B Eymin, O Micheau, L Chaperot, J Plumas… in Cell Death & Differentiation (2006)

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