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  1. No Access

    Article

    Sumoylation of ING2 regulates the transcription mediated by Sin3A

    ING2 (inhibitor of growth 2) is a candidate tumor-suppressor gene involved in cell cycle control, apoptosis and senescence. Although the functions of ING2 within the chromatin remodeling complex Sin3A/histone ...

    D Ythier, D Larrieu, R Binet, O Binda, C Brambilla, S Gazzeri, R Pedeux in Oncogene (2010)

  2. No Access

    Article

    The adenovirus E4orf4 protein induces growth arrest and mitotic catastrophe in H1299 human lung carcinoma cells

    The human adenovirus E4orf4 protein, when expressed alone, induces p53-independent death in a wide range of cancer cells. Earlier studies by our groups suggested that although in some cases cell death can be a...

    S Li, A Szymborski, M-J Miron, R Marcellus, O Binda, J N Lavoie, P E Branton in Oncogene (2009)

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    Article

    SIRT1 negatively regulates HDAC1-dependent transcriptional repression by the RBP1 family of proteins

    Both RBP1 and the highly related protein BCAA play a role in the induction of growth arrest and cellular senescence via mechanisms involving transcriptional repression. While investigating the transcriptional ...

    O Binda, C Nassif, P E Branton in Oncogene (2008)