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    Article

    Production of growth factors related to fibroblast growth factor and platelet-derived growth factor by human embryonal carcinoma cells

    Previous studies have demonstrated that mouse embryonal carcinoma (EC) cells produce at least two growth factors: one related to platelet-derived growth factor (PDGF) and another related to basic fibroblast gr...

    Jay Tiesman, Anita Meyer, Ronald N. Hines in In Vitro Cellular & Developmental Biology (1988)

  2. Article

    VARIATION IN INDUCTION OF PLACENTAL CYTOCHROME P4502E1: POSSIBLE ROLE IN SUSCEPTIBILITY TO FETAL ALCOHOL SYNDROME? • 484

    Abdur Rasheed, Ronald N Hines, D. Gail McCarver-Mav in Pediatric Research (1996)

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    Article

    Developmental regulation of the L-type calcium channel α1C subunit expression in heart

    We used Northern analyses, RNase protection assays and immunoblot analyses to examine the relationship among developmental age of the heart, abundance of mRNA and L-type calcium channel α1Csubunit protein, and to...

    Lei Leu, Donald S. O'Hara, Steven E. Cala in Molecular and Cellular Biochemistry (2000)

  4. Article

    Human Hepatic Flavin-Containing Monooxygenases 1 (FMO1) and 3 (FMO3) Developmental Expression

    The flavin-containing monooxygenases (FMOs) are important for the metabolism of numerous therapeutics and toxicants. Six mammalian FMO genes (FMO1–6) have been identified, each exhibiting developmental and tissue...

    Sevasti B Koukouritaki, Pippa Simpson, Catherine K Yeung in Pediatric Research (2002)

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    Article

    Population-Based Analysis of Methadone Distribution and Metabolism Using an Age-Dependent Physiologically Based Pharmacokinetic Model

    Limited pharmacokinetic (PK) and pharmacodynamic (PD) data are available to use in methadone dosing recommendations in pediatric patients for either opioid abstinence or analgesia. Considering the extreme inte...

    Feng Yang, ** Tong, D. Gail. McCarver in Journal of Pharmacokinetics and Pharmacody… (2006)

  6. Article

    Ontogeny of plasma proteins, albumin and binding of diazepam, cyclosporine, and deltamethrin

    To characterize the ontogeny of plasma albumin and total proteins, due to the lack of a comprehensive pediatric database. Secondly, to establish the magnitude and duration of maturational changes in binding of...

    Pankaj K. Sethi, Catherine A. White, Brian S. Cummings in Pediatric Research (2016)