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Article
Open AccessInhibition of glypican-1 expression induces an activated fibroblast phenotype in a human bone marrow-derived stromal cell-line
Cancer-associated fibroblasts (CAFs) are the most abundant stromal cell type in the tumor microenvironment. CAFs orchestrate tumor-stromal interactions, and contribute to cancer cell growth, metastasis, extrac...
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Article
Open AccessIdentification of lipidomic profiles associated with drug-resistant prostate cancer cells
The association of circulating lipids with clinical outcomes of drug-resistant castration-resistant prostate cancer (DR-CRPC) is not fully understood. While it is known that increases in select lipids correlat...
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Article
Open AccessParadoxical Role of Glypican-1 in Prostate Cancer Cell and Tumor Growth
Recent studies suggest that glypican-1 (GPC-1) is a biomarker for prostate cancer, but there are few studies elucidating the role of GPC-1 in prostate cancer progression. We observed high expression of GPC-1 i...
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Article
Ontogeny of plasma proteins, albumin and binding of diazepam, cyclosporine, and deltamethrin
To characterize the ontogeny of plasma albumin and total proteins, due to the lack of a comprehensive pediatric database. Secondly, to establish the magnitude and duration of maturational changes in binding of...
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Article
Changes in mRNA and protein expression in the renal cortex of male and female F344 rats treated with bromate
Bromate (BrO3 −), a by-product of ozonation of drinking water, induces nephrotoxicity in male rats at much lower doses than in female rats. This difference appears to be related to the development...
