5 Result(s)
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Raphael Pineau
Cancer Research
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Article
Open AccessExperimental and computational modeling for signature and biomarker discovery of renal cell carcinoma progression
Renal Cell Carcinoma (RCC) is difficult to treat with 5-year survival rate of 10% in metastatic patients. Main reasons of therapy failure are lack of validated biomarkers and scarce knowledge of the biological...
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Article
Open AccessCorrection to: Orthotopic model of lung cancer: isolation of bone micro-metastases after tumor escape from Osimertinib treatment
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Article
Open AccessOrthotopic model of lung cancer: isolation of bone micro-metastases after tumor escape from Osimertinib treatment
Osimertinib is a third generation tyrosine kinase inhibitor (TKI) that targets the epidermal growth factor receptor (EGFR) in lung cancer. However, although this molecule is not subject to some of the resistan...
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Article
Open AccessHigh epiregulin expression in human U87 glioma cells relies on IRE1α and promotes autocrine growth through EGF receptor
Epidermal growth factor (EGF) receptors contribute to the development of malignant glioma. Here we considered the possible implication of the EGFR ligand epiregulin (EREG) in glioma development in relation to ...
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Article
Inhibition of FGF receptor activity in glioma implanted into the mouse brain using the tetracyclin-regulated expression system
We have investigated growth and vascularization of malignant glioma in mice upon conditional inhibition of fibroblast growth factor (FGF) receptor activity. C6 rat glioma cells were transfected with a dominant...
