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Article
ING2 tumor suppressive protein translocates into mitochondria and is involved in cellular metabolism homeostasis
ING2 (Inhibitor of Growth 2) is a tumor suppressor gene that has been implicated in critical biological functions (cell-cycle regulation, replicative senescence, DNA repair and DNA replication), most of which ...
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Article
Open AccessCorrection to: Orthotopic model of lung cancer: isolation of bone micro-metastases after tumor escape from Osimertinib treatment
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Article
Open AccessOrthotopic model of lung cancer: isolation of bone micro-metastases after tumor escape from Osimertinib treatment
Osimertinib is a third generation tyrosine kinase inhibitor (TKI) that targets the epidermal growth factor receptor (EGFR) in lung cancer. However, although this molecule is not subject to some of the resistan...
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Article
ING3 is required for ATM signaling and DNA repair in response to DNA double strand breaks
Inhibitor of Growth 3 (ING3) is a candidate tumor suppressor gene whose expression is lost in tumors such as hepatocellular carcinoma, head and neck squamous cell carcinoma and melanoma. In the present study, ...
