145 Result(s)
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Article
Open AccessRisks associated with global warming of 1.5 to 4 °C above pre-industrial levels in human and natural systems in six countries
The Topical Collection “Accrual of Climate Change Risk in Six Vulnerable Countries” provides a harmonised assessment of risks to human and natural systems due to global warming of 1.5–4 °C in six countries (Ch...
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Open AccessRigorous Asymptotics of a KdV Soliton Gas
We analytically study the long time and large space asymptotics of a new broad class of solutions of the KdV equation introduced by Dyachenko, Zakharov, and Zakharov. These solutions are characterized by a Rie...
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The changing spectrum of hypertension in premature infants
The objective is to document changes in the etiologic spectrum of hypertension in premature infants.
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Open AccessChanging molecular profile of brain metastases compared with matched breast primary cancers and impact on clinical outcomes
Breast cancer commonly metastasises to the brain, but little is known about changes in the molecular profile of the brain secondaries and impact on clinical outcomes.
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Article
Open AccessIs China ‘Crowding Out’ South African Exports of Manufactures?
This article analyses the impact of Chinese competition on South African manufacturing exports to its major markets in Europe, the United States and Sub-Saharan Africa. The article considers five related resea...
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Hepatic activation of irinotecan predicts tumour response in patients with colorectal liver metastases treated with DEBIRI: exploratory findings from a phase II study
The response of colorectal liver metastases to the cytotoxic agent irinotecan varies widely. Attempts to correlate tumour metabolism with response have been mixed. This study investigated the hepatic metabolis...
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Child sexual abuse reported by an English national sample: characteristics and demography
The 2007 adult psychiatric morbidity survey in England provides detailed information of high quality about sexual abuse. Given the major psychiatric implications of child sexual abuse (CSA), we aimed to establ...
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Charcot neuroarthropathy in diabetes mellitus
Charcot neuroarthropathy has been recognised for over 130 years and yet it remains a major cause of morbidity for patients with diabetes mellitus and a continuing challenge for physicians. It is rare but it s...
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Article
Suicide ideation in Chinese adolescents
Background The suicide rate in China is estimated to be around three times the global average, with women in the 15- to 24-year-old age group particularly vulnerable. Despite this, there is a dea...
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Germline mutations in the ribonuclease L gene in families showing linkage with HPC1
Although prostate cancer is the most common non-cutaneous malignancy diagnosed in men in the United States1,2, little is known about inherited factors that influence its genetic predisposition3,4,5. Here we repor...
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Collective approaches for the control of depression in England
Objective This paper addresses the prevention and treatment of depression in the general population. It argues that the public health burden of depression cannot be effectively tackled s...
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World Health Day 2001: minding the world's mental health
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Systems of Psychiatric Care: Principles and Desiderata of Good Services
Systems of psychiatric care can be conceived of as complex, multi-dimensional frameworks or matrices which do not exist in isolation but are firmly rooted in and influenced by prevailing mores, political clima...
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Psychiatric disorder and dysfunction in the UK National Survey of Psychiatric Morbidity
Background: Psychiatric symptoms are widespread in the general population, but have little effect on performance. Deficits in performance and psychiatric symptoms may be the end point of...
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Long-term treatment of acromegaly with the somatostatin analogue SR-lanreotide
Objective: To assess the efficacy and tolerability of SR-lanreotide in the treatment of active acromegaly. Patients and design: 30 patients (17 men and 13 women) were treated in whom active acromegaly was conf...
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Chapter
Psychiatrische Versorgungsstrukturen: Prinzipien und Voraussetzungen einer adäquaten Versorgung
Psychiatrische Versorgungsstrukturen stellen komplexe, multidimensio-nale Systeme oder Raster dar, die nicht unabhängig bestehen, sondern in allgemeinen Wertvorstellungen, dem politischen Klima und kulturellen...
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On The State of the Public Health : the annual report of the Chief Medical Officer of the Department of Health for England, 1995: an example of increased visibility of mental health at a national level
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Nations for Mental Health
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The National Survey of Psychiatric Morbidity in Great Britain
We have given a brief overview of the focus, objectives and methodology of the national psychiatric comorbidity survey of Great Britain, and the first reports of the results will follow shortly. The survey dat...
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Chapter
Immediate-early gene activation as a window on mechanism in the nervous system
Immediate early genes (IEGs) were originally described as a class of genes rapidly and transiently expressed in cells stimulated with growth factors without the requirement for de novo protein synthesis (Cochr...