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Article
Prospects for fundamental physics with LISA
In this paper, which is of programmatic rather than quantitative nature, we aim to further delineate and sharpen the future potential of the LISA mission in the area of fundamental physics. Given the very broa...
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Article
The optical afterglow of the short gamma-ray burst associated with GW170817
The binary neutron star merger GW170817 was the first multi-messenger event observed in both gravitational and electromagnetic waves1,2. The electromagnetic signal began approximately two seconds post-merger with...
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Article
Open AccessMUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target
MUC13 is a transmembrane mucin glycoprotein that is over produced by many cancers, although its functions are not fully understood. Nuclear factor-κB (NF-κB) is a key transcription factor promoting cancer cell...
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Article
The MUC1 mucin specifically inhibits activation of the NLRP3 inflammasome
MUC1 is a cell membrane-associated mucin, expressed ubiquitously on the mucosal epithelia as well as by immune cells, that limits the inflammatory response to multiple pathogens. We have recently shown that MU...
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Chapter and Conference Paper
Investigation, Using CMAQ, of Sensitivity of Air Quality Modelling to Input Ammonia Emissions
A comparison of the results from two independent CMAQ modelling systems for the same UK 2003 scenario suggests the need for improvement to temporal profiles of the input emissions data used by atmospheric models.
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Chapter and Conference Paper
Evaluation and Inter-comparison of Acid Deposition Models for the UK
An evaluation has been made of a range of simple and complex atmospheric transport models, applied to estimate sulphur and nitrogen deposition in the UK in order to provide information to policy makers to supp...
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Article
Hepatic activation of irinotecan predicts tumour response in patients with colorectal liver metastases treated with DEBIRI: exploratory findings from a phase II study
The response of colorectal liver metastases to the cytotoxic agent irinotecan varies widely. Attempts to correlate tumour metabolism with response have been mixed. This study investigated the hepatic metabolis...
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Article
Abstracts of presentations on selected topics at the xlvth international plant protection congress (IPPC) July 25–30, 1999
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Article
Different manifestations of Toxoplasma gondii infection in F344 and LEW rats
There is evidence that not only the immune status, but also the genetic predisposition of certain hosts influence the clinical outcome of Toxoplasma gondii infection. By far the majority of our knowledge on gene...
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Chapter
Towards vaccination: what progress?
At the time of the previous edition of this book, 2 years ago, many important pieces of information were available which indicated that an effective vaccine against Helicobacter pylori was a realistic possibility...
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Article
Lower limb compartment syndrome complicating pelvic pouch surgery
A 10-year-old boy who underwent prolonged pelvic surgery in the Lloyd-Davies position developed a postoperative lower limb compartment syndrome that was successfully treated by urgent fasciotomy. The clinical ...
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Article
Abstracts of papers Rational use of drugs
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Chapter and Conference Paper
Cavitation Effects at Megahertz Frequencies
This experimental programme, using plane travelling-wave ultrasound with the sample liquid in the first axial maximum of the acoustic far-field,, has the following objectives:-
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