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  1. Article

    Open Access

    Changing molecular profile of brain metastases compared with matched breast primary cancers and impact on clinical outcomes

    Breast cancer commonly metastasises to the brain, but little is known about changes in the molecular profile of the brain secondaries and impact on clinical outcomes.

    A H Thomson, J McGrane, J Mathew, J Palmer, D A Hilton… in British Journal of Cancer (2016)

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  2. Article

    Noninvasive Ventilation for the Management of Pulmonary Hypertension Associated with Congenital Heart Disease in Children

    The use of noninvasive ventilation to support children with secondary pulmonary hypertension has not previously been reported. We present four children with secondary pulmonary hypertension in association with...

    H. J. Bunn, P. Roberts, A. H. Thomson in Pediatric Cardiology (2004)

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  3. No Access

    Article

    Flucytosine dose requirements in a patient receiving continuous veno-venous haemofiltration

    A.H. Thomson, G. Shankland, C. Clareburt, S. Binning in Intensive Care Medicine (2002)

  4. Article

    Open Access

    Population pharmacokinetics in phase I drug development: a phase I study of PK1 in patients with solid tumours

    Doxorubicin pharmacokinetics were determined in 33 patients with solid tumours who received intravenous doses of 20–320 mg m–2 HPMA copolymer bound doxorubicin (PK1) in a phase I study. Since assay constraints li...

    A H Thomson, P A Vasey, L S Murray, J Cassidy, D Fraier… in British Journal of Cancer (1999)

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  5. No Access

    Article

    Methotrexate removal during haemodialysis in a patient with advanced laryngeal carcinoma

     A 62-year-old patient on long-term haemodialysis who developed an inoperable T2N3Mo squamous-cell carcinoma of the larynx was treated with weekly low-dose methotrexate (MTX) after failing to respond to radiother...

    A. H. Thomson, Margaret Daly, Janusz Knepil… in Cancer Chemotherapy and Pharmacology (1996)

  6. No Access

    Article

    The effect of food on the absorption of slow-release isosorbide-5-mononitrate tablets

    The influence of food on the absorption characteristics of slow release isosorbide-5-mononitrate tablets was investigated in 10 normal healthy volunteers.

    A. H. Thomson, S. H. K. Miller, S. T. Green… in European Journal of Clinical Pharmacology (1988)

  7. No Access

    Article

    A clinically significant interaction between ciprofloxacin and theophylline

    We report a case of theophylline toxicity following the co-administration of ciprofloxacin. Total theophylline clearance fell from 2.3 l·h−1 to 0.8 l·h−1 when ciprofloxacin was added to the treatment regimen and ...

    A. H. Thomson, G. D. Thomson, M. Hepburn… in European Journal of Clinical Pharmacology (1987)

  8. No Access

    Article

    Disopyramide in acute myocardial infarction: Problems with changing pharmacokinetics

    In the acute phase of myocardial infarction it is recognized that serum disopyramide concentrations may be lower than expected. This has generally been attributed to reduced oral bioavailability.

    H. L. Elliott, A. H. Thomson, S. M. Bryson in European Journal of Clinical Pharmacology (1986)

  9. Article

    COUGH: AN INDICATOR OF AIRWAY FUNCTION

    The flow-volume loop obtained during coughing resembles that during a forced vital capacity manoeuvre, with the maximal flow rate during forced expiration being exceeded by the peak flow of each cough effort. ...

    C S Beardsmore, A H Thomson, H Simpson in Pediatric Research (1985)

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